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NHMRC Clinical Trials Centre: Recent submissions

    • The Long-Term Intervention with Pravastatin in Ischemic Disease (LIPID) dataset 

      John, Simes
      Published 2024-02-23
      This dataset includes 9,014 participants receiving either pravastatin, 40 mg/day or placebo, with a total cholesterol level at baseline of 4.0 to 7.0 mmol/L (155 to 270 mg/dl) and with a history of acute myocardial infarction ...
      Dataset
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    • Controlled evaLuation of Angiotensin Receptor Blockers for COVID-19 respIraTorY Disease (CLARITY) dataset 

      Jardine, Meg
      Published 2024-02-23
      This dataset includes up to 787 participants receiving an oral angiotensin receptor blocker (no placebo per standard of care in Australia, and telmisartan in India) recruited from seventeen hospitals in India and Australia. ...
      Open Access
      Dataset
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    • Patterns of care and outcomes for a clinical cohort of patients with lung cancer (2016-2021): Report on the Embedding Research (and Evidence) in Cancer Healthcare – EnRICH Program 

      Brown, Bernadette (Bea); Boyer, Michael; Young, Jane; Chin, Venessa; Brown, Christopher; Eggins, Renee; Simes, Robert John
      Published 2023-10-19
      Despite advances in diagnosis and treatment, lung cancer continues to be the leading cause of cancer-related death in Australia. Survival outcomes remain disappointing with less than a quarter of patients (22%) alive five ...
      Open Access
      Report, Research
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    • VESPRO: Statistical Report 

      Gibbs, Emma; Brown, Chris; Gebski, Val
      Published 2023-06-29
      An individual patient data prospective meta-analysis (IPD_PMA) of selective internal radiation therapy (SIRT) versus sorafenib for advanced, locally advanced or recurrent hepatocellular carcinoma (HCC) of the SARAH and ...
      Open Access
      Report, Technical
      View
    • Benefits Of Oxygen Saturation Targeting Study (BOOST-II) dataset 

      Tarnow-Mordi, William
      Published 2023-06-27
      This dataset includes 1135 participants receiving either a lower (85 to 89%) or a higher (91 to 95%) oxygen-saturation range in 15 centres in Australia. Baseline data will include demographics, antenatal glucocorticoid ...
      Open Access
      Dataset
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