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NHMRC Clinical Trials Centre: Recent submissions

    • Impact of Educational Attainment on Health Outcomes in Moderate to Severe CKD 

      Morton, Rachael L.; Schlackow, Iryna; Staplin, Natalie; Gray, Alastair; Cass, Alan; Haynes, Richard; Emberson, Jonathan; Herrington, William; Landray, Martin J.; Baigent, Colin; Mihaylova, Borislava
      Published 2016
      Background The inverse association between educational attainment and mortality is well established, but its relevance to vascular events and renal progression in a population with chronic kidney disease (CKD) is less ...
      Open Access
      Article
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    • Advance Care Planning With Patients Who Have End-Stage Kidney Disease: A Systematic Realist Review 

      O'Halloran, Peter; Noble, Helen; Norwood, Kelly; Maxwell, Peter; Shields, Joanne; Fogarty, Damian; Murtagh, Fliss; Morton, Rachael; Brazil, Kevin
      Published 2018
      Abstract Context Patients with end-stage kidney disease have a high mortality rate and disease burden. Despite this, many do not speak with health care professionals about end-of-life issues. Advance care planning is ...
      Open Access
      Article
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    • GRADE equity guidelines 1: considering health equity in GRADE guideline development: introduction and rationale 

      Welch, Vivian A.; Akl, Elie A.; Guyatt, Gordon; Pottie, Kevin; Eslava-Schmalbach, Javier; Ansari, Mohammed T.; Beer, Hans de; Briel, Matthias; Dans, Tony; Dans, Inday; Hultcrantz, Monica; Jull, Janet; Katikireddi, Srinivasa Vittal; Meerpohl, Joerg; Morton, Rachael; Mosdol, Annhild; Petkovic, Jennifer; Schunemann, Holger J.; Sharaf, Ravi N.; Singh, Jasvinder A.; Stanev, Roger; Tonia, Thomy; Tristan, Mario; Vitols, Sigurd; Watine, Joseph; Tugwell, Peter
      Published 2017
      Objectives This article introduces the rationale and methods for explicitly considering health equity in the Grading of Recommendations Assessment, Development and Evaluation (GRADE) methodology for development of clinical, ...
      Open Access
      Article
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    • Estimating loss in capability wellbeing in the first year of the COVID‑19 pandemic: a cross‑sectional study of the general adult population in the UK, Australia and the Netherlands 

      Mitchell, Paul Mark; Morton, Rachael L.; Hiligsmann, Mickaël; Husbands, Samantha; Coast, Joanna
      Published 2022
      Objectives To estimate capability wellbeing lost from the general adult populations in the UK, Australia and the Netherlands in the first year of the COVID-19 pandemic and the associated social restrictions, including ...
      Open Access
      Article
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    • Barriers and facilitators to nurse-led advance care planning and palliative care practice change in primary healthcare: a qualitative study 

      Nagarajan, Srivalli V.; Lewis, Virginia; Halcomb, Elizabeth; Rhee, Joel; Morton, Rachael L.; Mitchell, Geoffrey K.; Tieman, Jennifer; Phillips, Jane L.; Detering, Karen; Gavin, Jennifer; Clayton, Josephine M.
      Published 2022
      Primary care settings are ideal for initiating advance care planning (ACP) conversations and assessing palliative and supportive care needs. However, time constraints and a lack of confidence to sensitively and efficiently ...
      Open Access
      Article
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