Browsing by author "Cheng, S"
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Effect of Inflow Conditioning for Dry Powder Inhalers
Singh, G; Lowe, A; Azeem, A; Cheng, S; Chan, HK; Walenga, R; Kourmatzis, APublished 2021The transport of pharmaceutical dry powder inside an optically accessible inhaler-like device is studied using both macro- and microscopic high-speed imaging. The investigation aims to systematically study the effect of ...Open AccessArticle -
Effects of respiratory rate on the fluid mechanics of a reconstructed upper airway
Burchell, C; Kourmatzis, A; Zhao, Y; Raco, J; Mekonnen, T; Chan, H-K; Cheng, SPublished 2022This study aims to utilise particle image velocimetry (PIV) techniques to investigate the time-dependant effects of respiratory rate in the extrathoracic airway, to show how they affect the flow field developed. There has ...Open AccessArticle -
Extending the range of back-lit imaging in two-phase flows using an interrogation window based method
Singh, G; Kourmatzis, A; Lowe, A; Masri, AR; Chan, HK; Cheng, SPublished 2021This paper introduces a novel image processing methodology to enable an extension of the range of applicability of the back-lit imaging method to provide the simultaneous measurement of size and velocity in turbulent flows ...Open AccessArticle -
Fluidization of lactose carrier powders through normally directed airflow: The effect of recirculation and particle size
Elserfy, K; Kourmatzis, A; Singh, G; Chan, HK; Cheng, SPublished 2021This study investigates the fluidization of lactose carriers from a powder bed subjected to a normal force in a channel flow using high-speed imaging, particle image velocimetry (PIV), and high-speed, long-distance microscopy ...Open AccessArticle -
Fragmentation dynamics of single agglomerate-to-wall impaction
Lowe, A; Singh, G; Chan, HK; Masri, AR; Cheng, S; Kourmatzis, APublished 2020The de-agglomeration characteristics of single agglomerate-wall impaction are examined using high-resolution shadowgraph imaging. Experiments are performed to investigate the effects of constituent particle size (D50 from ...Open AccessArticle -
From laminar to turbulent flow in a dry powder inhaler: the effect of simple design modifications
SIngh, G; Tang, P; Cheng, S; Chan, H-K; Kourmatzis, APublished 2022In order to better understand powder dispersion in dry powder inhaler (DPI) devices, a new powder disperser was designed, which uses flow modifiers to alter powder fluidization behavior so as to physically replicate ...Open AccessArticle -
Local dynamics of pharmaceutical powder fluidization using high speed long distance microscopy and particle image velocimetry
Elserfy, K; Cheng, S; Chan, HK; Kourmatzis, APublished 2021The local dynamics of fluidized pharmaceutical carrier powders in a turbulent channel flow was studied using particle image velocimetry (PIV) and High-speed, long-distance microscopy (HS-LDM). Four different lactose powders ...Open AccessArticle
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