Sydney Digital Theses (University of Sydney Access only): Recent submissions
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Validation of surrogate endpoints used in clinical trials of immune checkpoint inhibitors and targeted therapies in advanced cancers
Published 2023This thesis evaluated the validity of surrogate endpoints used in trials of immune checkpoint inhibitors (ICIs) and molecular targeted therapies in advanced cancers. Many recent regulatory approvals of these novel agents ...USyd AccessThesis -
Implementation of the Early Diagnosis of Cerebral Palsy Guidelines: Exploring E-Learning for Practice Change and Improved Patient Outcomes
Published 2023Background: Health professionals can provide an early cerebral palsy (CP) diagnosis and intervention in a critical neuroplastic window, but late diagnosis and generic intervention are common. Clinical guidelines must be ...USyd AccessThesis -
Innovative Evidence-Based Assessment and Treatment of Oropharyngeal Dysphagia and Communication Disorders in Infants and Young Children at High Risk of Cerebral Palsy
Published 2023Infants with cerebral palsy (CP) have concomitant feeding and communication disorders with lifelong detrimental consequences, including premature death. Early detection and intervention for these deficits is under-researched. ...USyd AccessThesis -
Investigation of Polyvinylidene fluoride (PVDF) membrane contactors for ammonia removal with improved physico-chemical stability
Published 2023Hollow fibre membrane contactors (HFMCs) offer a new, sustainable, and compact way of recycling ammonia from wastewater. The limitations of current membrane contactors are i) low transfer flux ii) not chemically resistant ...USyd AccessThesis -
Paediatric pneumonia; Deriving a model of disease severity and the management of complicated pneumonia.
Published 2023The clinical questions raised in managing children with paediatric pneumonia have informed the research questions presented in this thesis. Is it possible to identify the child with pneumonia who is most at risk of severe ...USyd AccessThesis