Sydney Digital Theses (University of Sydney Access only): Recent submissions
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Antibody–Drug Conjugates: An Integrative Translational and Evidence Framework
Published 2026Background This thesis examined how antibody–drug conjugates (ADCs) can be designed to maximize benefit while minimizing toxicity. It focused on B cell maturation antigen (BCMA)-directed ADCs in multiple myeloma, ...USyd AccessThesis -
Platelet biomarkers of thrombotic risk in type 2 diabetes
Published 2026Platelet hyperreactivity contributes to the increased cardiovascular risk in type 2 diabetes mellitus (T2DM), yet its molecular basis is incompletely defined. The platelet endoplasmic reticulum (ER) is central to calcium ...USyd AccessThesis -
Microstructural evolution and mechanical properties of dissimilar structures manufactured by additive manufacturing
Published 2026The joining of dissimilar metals is vital in aerospace, electronics, and energy systems, where combining materials with complementary properties enhances component performance. Conventional fusion welding often struggles ...USyd AccessThesis -
Exploring Enhanced Visual Representation Learning for Improved Generative Modeling
Published 2025Image generation is a pivotal research direction in computer vision due to its wide-ranging potential applications. Despite substantial advances brought by the development of generative paradigms and network architectures, ...USyd AccessThesis -
Development of Endothelialised Microfluidic Platform for Cancer invasion and Thrombosis
Published 2026Thrombosis is a complex process involving vascular injury, platelet activation, and coagulation cascades, contributing to major clinical complications including myocardial infarction, stroke, and cancer-associated thrombosis ...USyd AccessThesis