Sydney Digital Theses (University of Sydney Access only): Recent submissions
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Myelin lipid metabolism in brain ageing and carriers of dementia risk alleles
Published 2024Ageing is the greatest risk factor for Alzheimer’s disease (AD) and dementia overall. Apolipoprotein E (ApoE) is the major lipid transport protein in the brain, and inheritance of the e4 allele of the APOE gene (APOE4) is ...USyd AccessThesis -
Inositol polyphosphate kinases: Investigating their function and targeting potential for new antifungal drug development
Published 2024Invasive fungal infections kill ~1.5 million people annually. Existing drugs target the cell wall and ergosterol but have drawbacks including toxicity and a narrow efficacy range. Resistance is also emerging. Our aim is ...USyd AccessThesis -
Optimal Operation Strategies for Economically Efficient and Reliable Peer-to-Peer Energy Markets in Regional Virtual Power Plants
Published 2024This Thesis comprehensively studies a novel integration approach for the economically efficient optimisation and operation of centralised regional virtual power plants (VPPs) by combining a holistic peer-to-peer (P2P) ...USyd AccessThesis -
CRISPR Screening in Expanded Phenotypic Space
Published 2024The use of CRISPR-Cas systems in genetic screening has permitted rapid functional annotation of the genome. However, conventional pooled CRISPR screening is constrained in several ways, including: (1) limited diversity of ...USyd AccessThesis -
Politics, Intellectuals and Walled Villages in Modern China 1852-1937
Published 2024This thesis will show that, within the modern political discourse applied to China, walled villages were inevitably involved in a long-term state-building process in the Republican period, which aimed to modernize China ...USyd AccessThesis