Sydney Digital Theses (University of Sydney Access only): Recent submissions
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Detection and understanding the role of Ultraviolet Radiation in Keratoconus
Published 2024Introduction Keratoconus is an eye disorder characterised by progressive corneal thinning and steepening of the cornea leading to impairment in vision and decreased quality of life. The detection of disease at its early ...USyd AccessThesis -
Cerebrospinal Fluid Proteomics: Unlocking Pathways in Paediatric Brain Diseases
Published 2024Encephalitis, Aicardi-Goutières syndrome (AGS), and autism spectrum disorder (ASD) are disabling childhood brain conditions. Despite distinct pathophysiology, neuroinflammation may be a converging factor. This study examined ...USyd AccessThesis -
Improving Health Services Delivery for Better Outcomes for Aboriginal and Torres Strait Islander Children
Published 2024Objectives: To identify and describe the outcomes of health services for Aboriginal and Torres Strait Islander children valued by stakeholders, and to elicit the preferences of stakeholders for characteristics of health ...USyd AccessThesis -
Toll like receptor 2 mediated alpha synuclein pathology in Parkinsons disease
Published 2023α-Synuclein (αSyn) plays a critical role in the pathogenesis of Parkinson's disease (PD). Initially, it was thought to exist exclusively within cells. However, evidence suggests its presence in cerebrospinal fluid, plasma, ...USyd AccessThesis -
Monocyte Functional and Metabolic Re-Programming Induced by Oxidized LDL
Published 2024Background: Dyslipidaemia affects 2 in 3 adult Australians and increases the lifetime risk of atherosclerotic cardiovascular diseases (ASCVDs). The stability of atherosclerotic lesions is associated with macrophage phenotype, ...USyd AccessThesis