Browsing Sydney Digital Theses (University of Sydney Access only) by subject "targeted therapies"
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CANCER CLINICAL TRIAL DESIGN IN THE ERA OF TARGETED AND IMMUNOLOGICAL THERAPIES
Published 2019-02-18The aim of this thesis was to understand and improve the design of clinical trials testing targeted and immunological anticancer therapies. My systematic review of contemporary phase 3 trials of targeted and immunological ...Thesis -
Estimating and communicating survival times to patients with incurable cancer who are treated with targeted therapies
Published 2020-01-01The aim of this thesis was to help oncologists estimate and communicate survival times to patients with incurable cancer receiving targeted therapies. For patients with incurable cancer receiving chemotherapy, simple ...Thesis -
A framework for extrapolating evidence for targeted therapies in rare biomarker-defined cancers
Published 2022This thesis aimed to develop an approach to assess the clinical benefit of targeted therapies for rare cancers. Despite claims that targeted therapies are superior based on strong biological rationale, a review of randomised ...Thesis