• A Novel Purification Procedure for Active Recombinant Human DPP4 and the Inability of DPP4 to Bind SARS-CoV-2 

      Xi, C.R.; Di Fazio, A.; Nadvi, N.A.; Patel, K.; Xiang, M.S.W.; Zhang, H.E.; Deshpande, C.; Low, J.K.K.; Wang, X.T.; Chen, Y.; McMillan, C.L.D.; Isaacs, A.; Osborne, B.; Vieira de Ribeiro, A.J.; McCaughan, G.W.; Mackay, J.P.; Church, W.B.; Gorrell, M.D.
      Published 2020
      Proteases catalyse irreversible posttranslational modifications that often alter a biological function of the substrate. The protease dipeptidyl peptidase 4 (DPP4) is a pharmacological target in type 2 diabetes therapy ...
      Article
    • Skin protective and regenerative effects of RM191A, a novel superoxide dismutase mimetic 

      Shariev, A.; Menounos, S.; Laos, A.J.; Laxman, P.; Lai, D.; Hua, S.; Zinger, A.; McRae, C.R.; Casbolt, L.S.; Combes, V.; Smith, G.; Hung, T.-T.; Dixon, K.M.; Thordarson, P.; Mason, R.S.; Das, A.
      Published 2021
      Superoxide dismutase (SOD) is known to be protective against oxidative stress-mediated skin dysfunction. Here we explore the potential therapeutic activities of RM191A, a novel SOD mimetic, on skin. RM191A is a water-soluble ...
      Article
    • The challenge for koala conservation on private land: koala habitat use varies with season on a fragmented rural landscape 

      Dargan, Jessica R.; Moriyama, Mika; Mella, Valentina S. A.; Lunney, Daniel; Crowther, Mathew S.
      Published 2019
      Land clearing for agriculture results in fragmented landscapes with diminished resources for wildlife. Habitat loss and fragmentation are widespread problems; however, their impacts are rarely assessed simultaneously at ...
      Open Access
      Article
    • Blood molecular markers associated with COVID-19 immunopathology and multi?organ damage 

      Chen, Yan‐Mei; Zheng, Yuanting; Yu, Ying; Wang, Yunzhi; Huang, Qingxia; Qian, Feng; Sun, Lei; Song, Zhi‐Gang; Chen, Ziyin; Feng, Jinwen; An, Yanpeng; Yang, Jingcheng; Su, Zhenqiang; Sun, Shanyue; Dai, Fahui; Chen, Qinsheng; Lu, Qinwei; Li, Pengcheng; Ling, Yun; Yang, Zhong; Tang, Huiru; Shi, Leming; Jin, Li; Holmes, Edward C.; Ding, Chen; Zhu, Tong‐Yu; Zhang, Yong‐Zhen
      Published 2020
      COVID-19 is characterised by dysregulated immune responses, metabolic dysfunction and adverse effects on the function of multiple organs. To understand host responses to COVID-19 pathophysiology, we combined transcriptomics, ...
      Article
    • Prevalence of cryptococcal antigenemia and nasal colonization in a free-ranging koala population 

      Schmertmann, Laura J.; Kan, Alex; Mella, Valentina S.A.; Fernandez, Cristina M.; Crowther, Mathew S.; Madani, George; Malik, Richard; Meyer, Wieland; Krockenberger, Mark B.
      Published 2019
      Cryptococcosis, caused by environmental fungi in the Cryptococcus neoformans and Cryptococcus gattii species complexes, affects a variety of hosts, including koalas (Phascolarctos cinereus). Cryptococcal antigenemia and ...
      Open Access
      Article