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Improving decision-making: Deriving patient-valued utilities from a disease-specific quality of life questionnaire for evaluating clinical trials
Published 2009-09-01
The aim of the work reported in this thesis was to develop a scoring algorithm that converts ratings from a validated disease-specific quality of life questionnaire called the Utility-Based Questionnaire-Cancer (UBQ-C) ...
Open Access
Thesis
DETECTION OF DELIRIUM IN HOSPITALISED CANCER PATIENTS
Published 2018-04-30
Delirium is an important syndrome associated with poor outcomes for patients, carers and staff. The incidence and prevalence of delirium in people with cancer in the hospital in-patient setting, is not established. The few ...
Open Access
Thesis
Citrus Peel in Maintaining Cellular Quiescence of Prostate Cancer
Published 2019-02-11
Cancer recurrence remains a major concern for cancer patients despite the significant advancement in cancer treatment. Cell cycle re-entry of quiescent cancer cells has been implicated as a key factor for cancer recurrence. ...
Open Access
Thesis
Growing up with cancer: A qualitative study of the impact of cancer on the experience of growing up
Published 2012-01-01
Because more young people are surviving cancer than ever before, more young people than ever before are living with the physical, psychological, emotional and social consequences of cancer illness and treatment. They do ...
Open Access
Thesis
Biology and enzymatic cleavage of ferlins: from membrane repair to cancer
Published 2018-01-13
Enzymatic cleavage can modify the function of target proteins. In this thesis I investigate the enzymatic cleavage of myoferlin and dysferlin, two members of the ferlin family. In response to membrane injury, dysferlin is ...
Open Access
Thesis
Living on: A qualitative study of the experience of living with multiple myeloma
Published 2013-01-07
This thesis aims to provide a rich, empirically grounded understanding of what it is like to live with myeloma after the first relapse, in ‘the era of novel agents’. This was achieved by exploring the experience of both ...
Open Access
Thesis
A population-based examination of cancer in New South Wales farm residents compared to rural non-farm and urban residents
Published 2017-02-14
The cancer indicators and outcomes of rural Australians are generally less favourable than those of their urban counterparts, but the situation for farm residents is less well known. With a focus on farm residents, this ...
Open Access
Thesis
A study of lymphoma in Bullmastiff dogs
Published 2019-06-14
Lymphoma is the most common cancer in Bullmastiffs and Bullmastiff is one of the breeds that are the most predisposed to lymphoma. The investigation of the population and genome started with the notice of high incidence ...
USyd Access
Thesis
The LMO4-DEAF1 complex and its biological impacts
Published 2013-10-14
LIM domains are non-classical zinc fingers that bind other proteins. They have diverse cellular functions that range from regulating gene expression to maintaining the structural integrity of the cell. LIM domain-only ...
USyd Access
Thesis
The experience of long-term survival following allogeneic blood and marrow transplant (BMT) in New South Wales (NSW), Australia
Published 2018-12-20
Allogeneic blood and marrow transplant (BMT) is widely used for the treatment of life threatening malignant and non-malignant diseases in both adults and children. While it provides many patients with their best opportunity ...
Open Access
Thesis