Aging and the hepatic disposition of nanoparticles and nanomedicines

Lockwood, Glen Philip

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Open Access

Field	Value	Language
dc.contributor.author	Lockwood, Glen Philip
dc.date.accessioned	2025-06-25T01:04:21Z
dc.date.available	2025-06-25T01:04:21Z
dc.date.issued	2025	en
dc.identifier.uri	https://hdl.handle.net/2123/34031
dc.description.abstract	The liver and its sinusoidal endothelial cells have a major role in the disposition of nanosubstrates. This is significant for understanding the effects of aging on the liver and susceptibility to some age- related diseases; and for the therapeutic effects of nanomedicines that target the liver. This is a hybrid thesis consisting of publications and non-published studies with the overarching aim of studying the role of the liver and aging of the liver on the behaviour of nanoparticles (NPs) including nanomedicines.	en
dc.language.iso	en	en
dc.subject	Liver	en
dc.subject	Quantum dot	en
dc.subject	Nanoparticle	en
dc.subject	Amyloid	en
dc.subject	Human Growth Hormone	en
dc.subject	Interferon	en
dc.title	Aging and the hepatic disposition of nanoparticles and nanomedicines	en
dc.type	Thesis
dc.type.thesis	Doctor of Philosophy	en
dc.rights.other	The author retains copyright of this thesis. It may only be used for the purposes of research and study. It must not be used for any other purposes and may not be transmitted or shared with others without prior permission.	en
usyd.faculty	SeS faculties schools::Faculty of Medicine and Health	en
usyd.department	Concord Clinical School	en
usyd.degree	Doctor of Philosophy Ph.D.	en
usyd.awardinginst	The University of Sydney	en
usyd.advisor	Cogger, Victoria
usyd.include.pub	No	en