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dc.contributor.authorHalawani, Aleen Al
dc.date.accessioned2024-09-03T05:08:24Z
dc.date.available2024-09-03T05:08:24Z
dc.date.issued2024en_AU
dc.identifier.urihttps://hdl.handle.net/2123/33043
dc.description.abstractThe diverse roles of tropoelastin in various cellular processes has garnered interest due to its potential therapeutic applications. This work aimed to investigate the effects of tropoelastin on bone marrow-derived mesenchymal stromal cells (BM-MSCs) and fibroblasts to elucidate the underlying mechanisms for its demonstrated benefits.en_AU
dc.language.isoenen_AU
dc.subjectStem Cellsen_AU
dc.subjectStromal Cellsen_AU
dc.subjectMultiomicsen_AU
dc.subjectSingle Cell RNA-Seqen_AU
dc.subjectsnATAC-Seqen_AU
dc.subjectGene Regulationen_AU
dc.subjectMatrix Proteinsen_AU
dc.titleBioinformatics-based Analysis of Gene Expression and Chromatin Accessibility Changes in Cells Treated with Tropoelastinen_AU
dc.typeThesis
dc.type.thesisDoctor of Philosophyen_AU
dc.rights.otherThe author retains copyright of this thesis. It may only be used for the purposes of research and study. It must not be used for any other purposes and may not be transmitted or shared with others without prior permission.en_AU
usyd.facultySeS faculties schools::Faculty of Science::School of Life and Environmental Sciencesen_AU
usyd.degreeDoctor of Philosophy Ph.D.en_AU
usyd.awardinginstThe University of Sydneyen_AU
usyd.advisorWeiss, Anthony


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