Bioinformatics-based Analysis of Gene Expression and Chromatin Accessibility Changes in Cells Treated with Tropoelastin

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Field	Value	Language
dc.contributor.author	Halawani, Aleen Al
dc.date.accessioned	2024-09-03T05:08:24Z
dc.date.available	2024-09-03T05:08:24Z
dc.date.issued	2024	en
dc.identifier.uri	https://hdl.handle.net/2123/33043
dc.description.abstract	The diverse roles of tropoelastin in various cellular processes has garnered interest due to its potential therapeutic applications. This work aimed to investigate the effects of tropoelastin on bone marrow-derived mesenchymal stromal cells (BM-MSCs) and fibroblasts to elucidate the underlying mechanisms for its demonstrated benefits.	en
dc.language.iso	en	en
dc.rights	The author retains copyright of this thesis
dc.subject	Stem Cells	en
dc.subject	Stromal Cells	en
dc.subject	Multiomics	en
dc.subject	Single Cell RNA-Seq	en
dc.subject	snATAC-Seq	en
dc.subject	Gene Regulation	en
dc.subject	Matrix Proteins	en
dc.title	Bioinformatics-based Analysis of Gene Expression and Chromatin Accessibility Changes in Cells Treated with Tropoelastin	en
dc.type	Thesis
dc.type.thesis	Doctor of Philosophy	en
dc.rights.other	The author retains copyright of this thesis. It may only be used for the purposes of research and study. It must not be used for any other purposes and may not be transmitted or shared with others without prior permission.	en
usyd.faculty	SeS faculties schools::Faculty of Science::School of Life and Environmental Sciences	en
usyd.degree	Doctor of Philosophy Ph.D.	en
usyd.awardinginst	The University of Sydney	en
usyd.advisor	Weiss, Anthony