Bioinformatics-based Analysis of Gene Expression and Chromatin Accessibility Changes in Cells Treated with Tropoelastin
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Open Access
Type
ThesisThesis type
Doctor of PhilosophyAuthor/s
Halawani, Aleen AlAbstract
The diverse roles of tropoelastin in various cellular processes has garnered interest due to its
potential therapeutic applications. This work aimed to investigate the effects of tropoelastin on bone
marrow-derived mesenchymal stromal cells (BM-MSCs) and fibroblasts to elucidate the underlying
mechanisms for its demonstrated benefits.The diverse roles of tropoelastin in various cellular processes has garnered interest due to its
potential therapeutic applications. This work aimed to investigate the effects of tropoelastin on bone
marrow-derived mesenchymal stromal cells (BM-MSCs) and fibroblasts to elucidate the underlying
mechanisms for its demonstrated benefits.
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Date
2024Rights statement
The author retains copyright of this thesis. It may only be used for the purposes of research and study. It must not be used for any other purposes and may not be transmitted or shared with others without prior permission.Faculty/School
Faculty of Science, School of Life and Environmental SciencesAwarding institution
The University of SydneyShare