Suicide by poisoning in Australia: patterns of medicine use and targets for means restriction
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USyd Access
Type
ThesisThesis type
Doctor of PhilosophyAuthor/s
Lim, Jessy SheiwayAbstract
Suicide prevention remains a major health priority, with many risk factors and influences being
complex and varied among individuals. A range of suicide prevention strategies should be used to
address each of these factors, and a knowledge of different suicide methods can ...
See moreSuicide prevention remains a major health priority, with many risk factors and influences being complex and varied among individuals. A range of suicide prevention strategies should be used to address each of these factors, and a knowledge of different suicide methods can help develop targeted interventions. Recommendations to reduce suicide by poisoning first require identification of poisons used for suicide in the population. Characteristics and trends of these suicides should also be monitored. Medicines treat medical conditions that pre-dispose suicide risk, while the choice and availability of medicines has an influence on what medicines can also be used for harm and intentional self-poisoning. National surveillance data for medicines and substances involved in poisoning suicides often do not provide a greater level of detail than drug class. There are also few studies that investigate both medicines and substances, including alcohol and illicit drugs, that were used preceding suicide at a national level. Identifying both through toxicological analysis can provide a better understanding of how medicines and substances are being used or combined in a high-risk population. Chapter 2 analysed national means restriction interventions to reduce public access to poisons from a global and historical perspective. The systematic review provided evidence that poisoning suicide rates were reduced by means restriction, with method substitution (other methods of suicide subsequently increasing) being unlikely. Chapters 3 and 4 identified medicines that were the most likely to be involved in suicides by poisonings. These medicines are recommended targets for means restriction or should be prescribed carefully. This means monitoring or limiting quantities and selecting these medicines as treatment options only after other medicines that are less toxic in overdose have been trialled or considered.
See less
See moreSuicide prevention remains a major health priority, with many risk factors and influences being complex and varied among individuals. A range of suicide prevention strategies should be used to address each of these factors, and a knowledge of different suicide methods can help develop targeted interventions. Recommendations to reduce suicide by poisoning first require identification of poisons used for suicide in the population. Characteristics and trends of these suicides should also be monitored. Medicines treat medical conditions that pre-dispose suicide risk, while the choice and availability of medicines has an influence on what medicines can also be used for harm and intentional self-poisoning. National surveillance data for medicines and substances involved in poisoning suicides often do not provide a greater level of detail than drug class. There are also few studies that investigate both medicines and substances, including alcohol and illicit drugs, that were used preceding suicide at a national level. Identifying both through toxicological analysis can provide a better understanding of how medicines and substances are being used or combined in a high-risk population. Chapter 2 analysed national means restriction interventions to reduce public access to poisons from a global and historical perspective. The systematic review provided evidence that poisoning suicide rates were reduced by means restriction, with method substitution (other methods of suicide subsequently increasing) being unlikely. Chapters 3 and 4 identified medicines that were the most likely to be involved in suicides by poisonings. These medicines are recommended targets for means restriction or should be prescribed carefully. This means monitoring or limiting quantities and selecting these medicines as treatment options only after other medicines that are less toxic in overdose have been trialled or considered.
See less
Date
2023Rights statement
The author retains copyright of this thesis. It may only be used for the purposes of research and study. It must not be used for any other purposes and may not be transmitted or shared with others without prior permission.Faculty/School
Faculty of Medicine and Health, School of Medical SciencesAwarding institution
The University of SydneyShare