Role of an isoflavone metabolite in prevention of skin cancer

Access status:

Open Access

Field	Value	Language
dc.contributor.author	Widyarini, Sitarina
dc.date.accessioned	2022-03-25T00:07:16Z
dc.date.available	2022-03-25T00:07:16Z
dc.date.issued	2002	en_AU
dc.identifier.uri	https://hdl.handle.net/2123/27847
dc.description	b26538039_v1	en_AU
dc.description.abstract	The aims of the experiments presented in this thesis were to investigate some aspects of chemoprevention by a topically applied isoflavone, equol, its mechanisms and, in particular, its effect on solar-simulated ultraviolet radiation (SSUV)-induced immunosuppression and subsequent development of skin cancer in hairless mouse skin (SkthR-l). A dose-dependent efficacy of equol at micromolar (pM) concentrations has been demonstrated to protect against SSUV-induced skin damage and development of skin cancer.	en_AU
dc.language.iso	en	en_AU
dc.subject	Skin -- Cancer	en_AU
dc.subject	Skin -- Cancer -- Prevention	en_AU
dc.subject	Skin -- Cancer -- Immunological aspects	en_AU
dc.subject	Immune response	en_AU
dc.subject	Isoflavones	en_AU
dc.title	Role of an isoflavone metabolite in prevention of skin cancer	en_AU
dc.type	Thesis
dc.type.thesis	Doctor of Philosophy	en_AU
dc.rights.other	The author retains copyright of this thesis. It may only be used for the purposes of research and study. It must not be used for any other purposes and may not be transmitted or shared with others without prior permission.	en_AU
usyd.degree	Doctor of Philosophy Ph.D.	en_AU
usyd.awardinginst	The University of Sydney	en_AU