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Faculty of Medicine and Health: Recent submissions

    • Trimming the fat: is there a health economic case for use of new lipid lowering drugs in chronic kidney disease? A scoping review. 

      Gallagher, A; Agresta, B; Smyth, B; Jardine, M; Ferro, C; Morton, RL
      Published 2021
      Background Individuals with chronic kidney disease (CKD) are at a very high risk for atherosclerotic cardiovascular disease (ASCVD). New lipid-lowering agents offer hope of improved outcomes where traditional agents have ...
      Open Access
      Article
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    • A real-time IGRT method using a Kalman filter framework to extract 3D positions from 2D projections. 

      Nguyen, Doan Trang; Keall, Paul; Booth, Jeremy; Shieh, Chun-Chien; Poulsen, Per; O'Brien, Ricky
      Published 2021
      Purpose.To estimate 3D prostate motion in real-time during irradiation from 2D prostate positions acquired from a kV imager on a standard linear accelerator utilising a Kalman filter (KF) framework. The advantage of this ...
      Open Access
      Article
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    • The first-in-human implementation of adaptive 4D cone beam CT for lung cancer radiotherapy: 4DCBCT in less time with less dose. 

      O'Brien, Ricky; Dillon, Owen; Lau, Benjamin; George, Armia; Smith, Sandie; Wallis, Andrew; Sonke, Jan-Jakob; Keall, Paul; Vinod, Shalini
      Published 2021
      Background and purpose: We present the first implementation of Adaptive 4D cone beam CT (4DCBCT) that adapts the image hardware (gantry rotation speed and kV projections) in response to the patient's real-time respiratory ...
      Open Access
      Article
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    • Adaptive CaRdiac cOne BEAm computed Tomography (ACROBEAT): Developing the next generation of cardiac cone beam CT imaging. 

      Reynolds, Tess; Dillon, Owen; Prinable, Joseph; Whelan, Brendan; Keall, Paul; O'Brien, Ricky
      Published 2021
      Purpose: An important factor when considering the use of interventional cone beam computed tomography (CBCT) imaging during cardiac procedures is the trade-off between imaging dose and image quality. Accordingly, Adaptive ...
      Open Access
      Article
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    • Toward real-time verification for MLC tracking treatments using time-resolved EPID imaging. 

      Zwan, Benjamin; Caillet, Vincent; Booth, Jeremy; Colvill, Emma; Fuangrod, Todsaporn; O'Brien, Ricky; Briggs, Adam; O'Connor, Daryl; Keall, Paul; Greer, Peter
      Published 2021
      Purpose: In multileaf collimator (MLC) tracking, the MLC positions from the original treatment plan are continuously modified to account for intrafraction tumor motion. As the treatment is adapted in real time, there is ...
      Open Access
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