Browsing Faculty of Medicine and Health by subject "0299 Other Physical Sciences"
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The Accuracy and Precision of the KIM Motion Monitoring System Used in the Multi-Institutional TROG 15.01 Stereotactic Prostate Ablative Radiotherapy With KIM (SPARK) Trial
Published 2019-01-01Purpose: Kilovoltage intrafraction monitoring (KIM) allows for real-time image guidance for tracking tumor motion in six-degrees-of-freedom (6DoF) on a standard linear accelerator. This study assessed the geometric accuracy ...Open AccessArticle -
The adaptation and investigation of cone-beam CT reconstruction algorithms for horizontal rotation fixed-gantry scans of rabbits.
Published 2021Fixed-gantry radiation therapy has been proposed as a low-cost alternative to the conventional rotating-gantry radiation therapy, that may help meet the rising global treatment demand. Fixed-gantry systems require gravitational ...Open AccessArticle -
Adaptive CaRdiac cOne BEAm computed Tomography (ACROBEAT): Developing the next generation of cardiac cone beam CT imaging.
Published 2021Purpose: An important factor when considering the use of interventional cone beam computed tomography (CBCT) imaging during cardiac procedures is the trade-off between imaging dose and image quality. Accordingly, Adaptive ...Open AccessArticle -
Anatomical Deformation Due to Horizontal Rotation: Towards Gantry-Free Radiation Therapy
Published 2019-01-01Gantry-free radiation therapy systems may be simpler and more cost effective, particularly for MRI-guided photon or hadron therapy. This study aims to understand and quantify anatomical deformations caused by horizontal ...Open AccessArticle -
Cardiac radioablation for atrial fibrillation: Target motion characterization and treatment delivery considerations.
Published 2021Purpose: The safe delivery of cardiac radioablation (CR) for atrial fibrillation (AF) is challenged by multi-direction target motion, cardiac rate variability, target proximity to critical structures, and the importance ...Open AccessArticle -
Close-range feature-based head motion tracking for MRI and PET-MRI
Published 2018Optical motion tracking systems are effective in measuring head motion during MRI and PET scans. However, most systems rely on tracking attached markers which can slip or move relative to the head. In this study, we aimed ...Open AccessConference paper -
Dosimetric impact of intrafraction rotations in stereotactic prostate radiotherapy: A subset analysis of the TROG 15.01 SPARK trial.
Published 2019-01-01Background and purpose: Accurate delivery of radiotherapy is critical to achieve optimal treatment outcomes. Interfraction translational IGRT is now standard, and intrafraction motion management is becoming accessible. ...Open AccessArticle -
Dual cardiac and respiratory gated thoracic imaging via adaptive gantry velocity and projection rate modulation on a linear accelerator: A Proof-of-Concept Simulation Study.
Published 2019-01-01Purpose: Cardiac motion is typically not accounted for during pretreatment imaging for central lung and mediastinal tumors. However, cardiac induced tumor motion averages 5.8 mm for esophageal tumors and 3-5 mm for some ...Open AccessArticle -
Evaluating reconstruction algorithms for respiratory motion guided acquisition
Published 2020Conventional thoracic 4DCBCT scans take 1320 projections over 4 min. This paper investigates which reconstruction algorithms best leverage Respiratory-Motion-Guided (RMG) acquisition in order to reduce scan time and dose ...Open AccessArticle -
Experimental characterisation of the magnetic field correction factor,k->B,for Roos chambers in a parallel MRI-linac.
Published 2022Objective. Reference dosimetry on an MRI-linac requires a chamber specific magnetic field correction factor,kB⃗.This work aims to measure the correction factor for a parallel plate chamber on a parallel MRI-linac. Approach. ...Open AccessArticle -
Extended Intraoperative Longitudinal 3-Dimensional Cone Beam Computed Tomography Imaging With a Continuous Multi-Turn Reverse Helical Scan.
Published 2022Objectives: Cone beam computed tomography (CBCT) imaging is becoming an indispensable intraoperative tool; however, the current field of view prevents visualization of long anatomical sites, limiting clinical utility. Here, ...Open AccessArticle -
First experimental evaluation of multi-target multileaf collimator tracking during volumetric modulated arc therapy for locally advanced prostate cancer.
Published 2021Purpose: Locally advanced and oligometastatic cancer patients require radiotherapy treatment to multiple independently moving targets. There is no existing commercial solution that can simultaneously track and treat multiple ...Open AccessArticle -
First experimental investigation of simultaneously tracking two independently moving targets on an MRI-linac using real-time MRI and MLC tracking
Published 2020Purpose: High quality radiotherapy is challenging in cases where multiple targets with independent motion are simultaneously treated. A real-time tumor tracking system that can simultaneously account for the motion of two ...Open AccessArticle -
The first-in-human implementation of adaptive 4D cone beam CT for lung cancer radiotherapy: 4DCBCT in less time with less dose.
Published 2021Background and purpose: We present the first implementation of Adaptive 4D cone beam CT (4DCBCT) that adapts the image hardware (gantry rotation speed and kV projections) in response to the patient's real-time respiratory ...Open AccessArticle -
FLASH radiotherapy: Newsflash or flash in the pan?
Published 2019-01-01No abstract. A point / counterpoint article on the merits of ultra-high dose rate radiation therapy.Open AccessArticle -
Geometric uncertainty analysis of MLC tracking for lung SABR.
Published 2020Purpose: The purpose of this work was to report on the geometric uncertainty for patients treated with multi-leaf collimator (MLC) tracking for lung SABR to verify the accuracy of the system. Methods: Seventeen patients ...Open AccessArticle -
Imaging of regional ventilation: Is CT ventilation imaging the answer? A systematic review of the validation data.
Published 2019-01-01Computed Tomography Ventilation Imaging (CTVI) is an experimental imaging modality that derives regional lung function information from non-contrast respiratory-correlated CT datasets. Despite CTVI being extensively studied ...Open AccessArticle -
Magnetic modeling of actively shielded rotating MRI magnets in the presence of environmental steel.
Published 2021Rotating MRI systems could enable novel integrated medical devices such as MRI-Linacs, MRI-xray-angiography systems, and MRI-proton therapy systems. This work aimed to investigate the feasibility of rotating actively ...Open AccessArticle -
Measurements of human tolerance to horizontal rotation within an MRI scanner: Towards gantry-free radiation therapy.
Published 2021Introduction: Recent advances in image guidance and adaptive radiotherapy could enable gantry-free radiotherapy using patient rotation. Gantry-free radiotherapy could substantially reduce the cost of radiotherapy systems ...Open AccessArticle -
MRI-guided cardiac-induced target motion tracking for atrial fibrillation cardiac radioablation.
Published 2021Background and purpose: Atrial fibrillation (AF) cardiac radioablation (CR) challenges radiotherapy tracking: multiple small targets close to organs-at-risk undergo rapid differential cardiac contraction and respiratory ...Open AccessArticle