The University of Sydney: Recent submissions
-
Significant cell uptake of Gd(III)-diphenylphosphoryl-diphenylphosphonium complexes: evidence for a new conformationally-dependent tumour cell targeting vector
Published 2023The synthesis, characterisation, and tumour cell uptake of six novel Gd(III)-diphenylphosphoryl-diphenylphosphonium complexes are reported. The propyl-linked Gd(III) complexes can accumulate inside human glioma cells at ...Open AccessArticle -
Selective delivery of remarkably high levels of gadolinium to tumour cells using an arsonium salt
Published 2021The use of a triphenylarsonium vector for tumour cell-targeting leads to a dramatic increase in Gd3+ uptake in human glioblastoma multiforme cells by up to an order of magnitude over the isosteric triarylphosphonium analogue, ...Open AccessArticle -
Optimization of Vancomycin Therapy in Neonatal Intensive Care Unit (NICU)
Published 2025Vancomycin is the first-line treatment for staphylococcal infections in neonates, yet safe and effective dosing remains difficult because of limited clinical data and major developmental differences in pharmacokinetics ...Open AccessThesis -
Toward Scalable and Generalisable Garment Simulation with Graph Neural Networks
Published 2025Realistic garment simulation is essential for applications such as film production, video games and fashion design. While physics-based methods remain dominant for their accuracy and generality, they rely on costly numerical ...Open AccessThesis -
Advancing understanding of prognosis in sarcoma through quantitative proteomic analysis
Published 2025Sarcoma is a rare and heterogeneous group of malignancies, often associated with poor prognosis. Advances in quantitative mass spectrometry-based technologies now enable cancer proteomes to be studied on an unprecedented ...USyd AccessThesis