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dc.contributor.authorDay, RO
dc.contributor.authorCohen, M
dc.contributor.authorColeshill, MJ
dc.contributor.authorGhinea, N
dc.contributor.authorLipworth, W
dc.contributor.authorMaher, CG
dc.contributor.authorLatimer, J
dc.contributor.authorLin, CWC
dc.contributor.authorMcLachlan, AJ
dc.date.accessioned2020-01-13T03:28:14Z
dc.date.available2020-01-13T03:28:14Z
dc.date.issued2019
dc.identifier.citationDay RO, Cohen M, Coleshill MJ, Ghinea N, Lipworth W, Maher CG, Latimer J, Lin CWC, McLachlan AJ. 2019. Is it ethical to prescribe paracetamol for low back pain and osteoarthritis? Lancet Rheumatology. Vol 1 e140. https://doi.org/10.1016/S2665-9913(19)30041-4en_AU
dc.identifier.urihttps://hdl.handle.net/2123/21655
dc.description.abstractDespite accumulating evidence indicating that paracetamol is no more efficacious than placebo for acute uncomplicated low back pain and symptomatic osteoarthritis, it is still prescribed for these conditions. This is likely due to perceived clinical improvement in pain observed when the medicine is taken and the known harms associated with pharmacological alternatives. The benefits observed in the majority of patients are, however, likely to be placebo effects. This scenario poses an ethical dilemma between respecting patient autonomy by providing complete information while also promoting clinical benefit (beneficence). This article discusses this situation and considers a framework in which paracetamol might continue to be prescribed for these conditions in an ethical manner, namely through discussing the evidence and the benefit that some patients experience from it.en_AU
dc.publisherElsevieren_AU
dc.relationNHMRC Career Development Fellowship (APP1036539)en_AU
dc.rights© 2019. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/en_AU
dc.subjectPlaceboen_AU
dc.subjectosteoarthritisen_AU
dc.subjectparacetamolen_AU
dc.subjectprescribingen_AU
dc.subjectethicsen_AU
dc.titleIs it ethical to prescribe paracetamol for acute low back pain and osteoarthritis?en_AU
dc.typeArticleen_AU
dc.subject.asrc2201 Applied ethicsen_AU
dc.subject.asrc1117 Public Health and Health Sciencesen_AU
dc.identifier.doi10.1016/S2665-9913(19)30041-4
dc.type.pubtypePost-printen_AU


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