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dc.contributor.authorPerkovic, V
dc.contributor.authorNeal, B
dc.date.accessioned2019-12-18
dc.date.available2019-12-18
dc.date.issued2012-12-27
dc.identifier.citationPerkovic V, Neal B. Trials in Kidney Disease — Time to EVOLVE. New England Journal of Medicine. 2012;367(26):2541-2542. doi:10.1056/nejme1212368en
dc.identifier.urihttps://hdl.handle.net/2123/21544
dc.description.abstractPatients with kidney disease face a substantially increased risk of cardiovascular events and death — one in five patients who are undergoing dialysis die each year in the United States. Elevated parathyroid hormone levels are almost universal in persons with advanced kidney failure and have been associated with these risks. Cinacalcet is an oral calcimimetic agent approved by the Food and Drug Administration (FDA) in 2004 for the treatment of secondary hyperparathyroidism in patients with dialysis-dependent kidney failure. Early reports supported the possibility that cinacalcet conferred cardiovascular protection and reduced fracture risk, although the statistical power of these studies . . .en
dc.language.isoen_AUen
dc.publisherMassachusetts Medical Societyen
dc.relationNHMRC GNT0571281, NHMRC GNT1003111en
dc.rightsOtheren
dc.titleTrials in Kidney Disease — Time to EVOLVEen
dc.typeArticleen
dc.identifier.doi10.1056/NEJMe1212368
dc.type.pubtypePublisher's versionen
dc.rights.otherFrom The New England Journal of Medicine, V Perkovic, B Neal, Trials in Kidney Disease — Time to EVOLVE, 367(26):2541-2542. Copyright © (2019) Massachusetts Medical Society. Reprinted with permission.en
usyd.facultyFaculty of Medicine and Health, Sydney Medical Schoolen


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