Recent Submissions

  • Trial of pregabalin for acute and chronic sciatica 

    Mathieson, S; Maher, CG; McLachlan, AJ; Latimer, J; Koes, BW; Hancock, MJ; Harris, I; Day, RO; Billot, L; Pik, J; Jan, S; Lin, CWC (New England Journal of Medicine, 2017-03-23)
    BACKGROUND: Sciatica can be disabling, and evidence regarding medical treatments is limited. Pregabalin is effective in the treatment of some types of neuropathic pain. This study examined whether pregabalin may reduce the ...
  • Modelling associations between neurocognition and functional course in young people with emerging mental disorders: a longitudinal cohort study 

    Crouse, Jacob; Chitty, Kate; Iorfino, Frank; Carpenter, Joanne; White, Django; Nichles, Alissa; Zmicerevska, Natalia; Guastella, Adam; Scott, Elizabeth; Lee, Rico; Naismith, Sharon; Scott, Jan; Hermens, Daniel; Hickie, Ian (Springer, 2020-01-21)
    Neurocognitive impairment is commonly associated with functional disability in established depressive, bipolar and psychotic disorders. However, little is known about the longer-term functional implications of these ...
  • The cyclic nitroxide antioxidant 4-methoxy-TEMPO decreases mycobacterial burden in vivo through host and bacterial targets 

    Black, Harrison; Xu, Wenbo; Hortle, Elinor; Robertson, Sonia; Britton, Warwick; Kaur, Amandeep; New, Elizabeth; Witting, Paul; Chami, Belal; Oehlers, Stefan (Elsevier, 2019-05-01)
    Tuberculosis is a chronic inflammatory disease caused by persistent infection with Mycobacterium tuberculosis. The rise of antibiotic resistant strains necessitates the design of novel treatments. Recent evidence shows ...
  • Mycobacterium marinum infection drives foam cell differentiation in zebrafish infection models 

    Johansen, Matt; Kasparian, Joshua; Hortle, Elinor; Britton, Warwick; Purdie, Auriol; Oehlers, Stefan (Developmental & Comparative Immunology, 2018-11)
    Host lipid metabolism is an important target for subversion by pathogenic mycobacteria such as Mycobacterium tuberculosis. The appearance of foam cells within the granuloma are well-characterised effects of chronic ...
  • Revisiting hypoxia therapies for tuberculosis 

    Oehlers, Stefan (Portland Press, 2019-06-17)
    The spectre of the coming post-antibiotic age demands novel therapies for infectious diseases. Tuberculosis, caused by Mycobacterium tuberculosis, is the single deadliest infection throughout human history. M. tuberculosis ...

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