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dc.contributor.authorSantos, Mary
dc.date.accessioned2019-06-17
dc.date.available2019-06-17
dc.date.issued2019-03-31
dc.identifier.urihttp://hdl.handle.net/2123/20578
dc.description.abstractBronchiectasis is a chronic lung disease that is characterised by excessive sputum production due to chronic airway inflammation. Physiotherapists use airway clearance techniques (ACTs) to assist with sputum clearance in people with bronchiectasis. Some of these techniques may involve positive expiratory pressure (PEP) devices. PEP devices provide a resistance to expiration which creates a back pressure in the airways which has been shown to enhance sputum clearance through stabilising the airways during expiration and improving alveoli filling via collateral channels. A simple PEP device, which is used in Australia, is the therapist-made bubble-PEP which is constructed from a container filled with water and tubing inserted into the container through which the patient expires. However, little is known about the physical properties of the bubble-PEP device or its effect on sputum clearance in patient populations. This PhD investigated: 1) the current use of the therapist-made bubble-PEP device by physiotherapists in public and private hospitals in Australia via an Australian-wide survey; 2) the pressures and oscillation frequencies generated by the therapist-made bubble-PEP device with variable air flows and tubing internal diameters via a benchtop laboratory study; 3) the pressures and oscillation frequencies generated by two versions of the therapist-made bubble-PEP devices compared to three commercially available bubble-PEP devices, via a benchtop laboratory study; and 4) whether the therapist made bubble-PEP device improved secretion clearance in people with bronchiectasis, when compared to the active cycle of breathing technique (an established ACT) or no intervention (control) in a randomised cross-over trial.en_AU
dc.publisherUniversity of Sydneyen_AU
dc.publisherFaculty of Health Sciencesen_AU
dc.rightsThe author retains copyright of this thesis. It may only be used for the purposes of research and study. It must not be used for any other purposes and may not be transmitted or shared with others without prior permission.en_AU
dc.subjectbubble-PEPen_AU
dc.subjectairway clearanceen_AU
dc.subjectphysiotherapyen_AU
dc.subjectbronchiectasisen_AU
dc.subjectpositive expiratory pressureen_AU
dc.subjectrespiratoryen_AU
dc.subject.otherincludes published articlesen_AU
dc.titleBubble-positive expiratory pressure device and effect on secretion clearance in people with bronchiectasisen_AU
dc.typePhD Doctorateen_AU
dc.type.pubtypeDoctor of Philosophy Ph.D.en_AU
dc.description.disclaimerAccess is restricted to staff and students of the University of Sydney . UniKey credentials are required. Non university access may be obtained by visiting the University of Sydney Library.en_AU


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