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dc.contributor.authorOborn, B
dc.contributor.authorGargett, MA
dc.contributor.authorCauser, TJ
dc.contributor.authorAlnaghy, SJ
dc.contributor.authorHardcastle, N
dc.contributor.authorMetcalfe, PE
dc.contributor.authorKeall, P
dc.date.accessioned2018-12-04
dc.date.available2018-12-04
dc.date.issued2017-12-01
dc.identifier.citationRadiother Oncol. 2017 Dec;125(3):433-438.en_AU
dc.identifier.urihttp://hdl.handle.net/2123/19614
dc.description.abstractBACKGROUND AND PURPOSE: To present experimental evidence of lung dose enhancement effects caused by strong inline magnetic fields. MATERIALS AND METHODS: A permanent magnet device was utilised to generate 0.95T-1.2T magnetic fields that encompassed two small lung-equivalent phantoms of density 0.3g/cm3. Small 6MV and 10MV photon beams were incident parallel with the magnetic field direction and Gafchromic EBT3 film was placed inside the lung phantoms, perpendicular to the beam (experiment 1) and parallel to the beam (experiment 2). Monte Carlo simulations of experiment 1 were also performed. RESULTS: Experiment 1: The 1.2T inline magnetic field induced a 12% (6MV) and 14% (10MV) increase in the dose at the phantom centre. The Monte Carlo modelling matched well (±2%) to the experimentally observed results. Experiment 2: A 0.95T field peaked at the phantom centroid (but not at the phantom entry/exit regions) details a clear dose increase due to the magnetic field of up to 25%. CONCLUSIONS: This experimental work has demonstrated how strong inline magnetic fields act to enhance the dose to lower density mediums such as lung tissue. Clinically, such scenarios will arise in inline MRI-linac systems for treatment of small lung tumours.en_AU
dc.publisherElsevieren_AU
dc.relationNHMRC 1112096, NHMRC 1036078en_AU
dc.rights© 2017. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/en_AU
dc.subjectMRI-linacen_AU
dc.subjectLung tumouren_AU
dc.titleExperimental verification of dose enhancement effects in a lung phantom from inline magnetic fields.en_AU
dc.typeArticleen_AU
dc.subject.asrcFoR::029903 - Medical Physicsen_AU
dc.identifier.doi10.1016/j.radonc.2017.09.012
dc.type.pubtypePost-printen_AU


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