• Fatty Acid Fueled Transmembrane Chloride Transport 

      Howe, Ethan N.W.; Gale, Philip A.
      Published 2019-06-21
      Generation of chemical gradients across biological membranes of cellular compartments is a hallmark of all living systems. Here we report a proof-of-concept prototype transmembrane pumping system in liposomes. The pump ...
      Open Access
      Article
    • C-BARQ Female dogs desexed non-behaivioural 2018 

      Starling, Melissa; Fawcett, Anne; Wilson, Bethany; Serpell, James; McGreevy, Paul
      Published 2019-10-01
      This dataset contains the variables from C-BARQ used to build models to predict the effects of proportion of life exposure to gonadal hormones on reported behaviour in the C-BARQ survey. It includes female dogs that were ...
      Open Access
      Dataset
    • Switchable DNA-origami nanostructures that respond to their environment and their applications 

      Daljit Singh, Jasleen Kaur; Tri Luu, Minh; Abbas, Ali; Wickham, Shelley F. J
      Published 2018-10-01
      Structural DNA nanotechnology, in which Watson-Crick base pairing drives the formation of self-assembling nanostructures, has rapidly expanded in complexity and functionality since its inception in 1981. DNA nanostructures ...
      Open Access
      Article
    • Anion carriers as potential treatments for cystic fibrosis: transport in cystic fibrosis cells, and additivity to channel-targeting drugs† 

      Li, Hongyu; Valkenier, Hennie; Thorne, Abigail G.; Dias, Christopher M.; Cooper, James A.; Kieffer, Marion; Busschaert, Nathalie; Gale, Philip A.; Sheppard, David N.; Davis, Anthony P.
      Published 2019-10-01
      Defective anion transport is a hallmark of the genetic disease cystic fibrosis (CF). One approach to restore anion transport to CF cells utilises alternative pathways for transmembrane anion transport, including artificial ...
      Open Access
      Article
    • The cerebellum in frontotemporal dementia: a meta-analysis of neuroimaging studies 

      Chen, Y.; Kumfor, F.; Landin-Romero, R.; Irish, Muireann; Piguet, O.
      Published 2019-08-19
      Frontotemporal dementia (FTD) is a neurodegenerative brain disorder primarily affecting the frontal and/or temporal lobes. Three main subtypes have been recognized: behavioural-variant FTD (bvFTD), semantic dementia (SD) ...
      Article