Maternal first trimester serum levels of free-beta human chorionic gonadotropin and male genital
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Open Access
Type
ArticleAuthor/s
Schneuer, FBower, C
Holland, A J A
Tasevski, V
Jamieson, S E
Barker, A
Lee, L
Majzoub, J A
Nassar, N
Abstract
Are maternal first trimester levels of serum free-beta hCG associated with the development of hypospadias or undescended testis (UDT) in boys? Overall, first trimester maternal levels of serum free-beta hCG are not associated with hypospadias or UDT. However, elevated levels were found in severe phenotypes (proximal hypospadias and bilateral UDT) suggesting an altered pathway of hormonal release in early pregnancy.Are maternal first trimester levels of serum free-beta hCG associated with the development of hypospadias or undescended testis (UDT) in boys? Overall, first trimester maternal levels of serum free-beta hCG are not associated with hypospadias or UDT. However, elevated levels were found in severe phenotypes (proximal hypospadias and bilateral UDT) suggesting an altered pathway of hormonal release in early pregnancy.
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Date
2016-08-01Publisher
Human ReproductionDepartment, Discipline or Centre
Menzies Centre for Health PolicyCitation
F.J. Schneuer, C. Bower, A.J.A. Holland, V. Tasevski, S.E. Jamieson, A. Barker, L. Lee, J.A. Majzoub, N. Nassar; Maternal first trimester serum levels of free-beta human chorionic gonadotrophin and male genital anomalies. Hum Reprod 2016; 31 (8): 1895-1903. doi: 10.1093/humrep/dew150Share