A randomised controlled trial of a code-word enuresis alarm
Field | Value | Language |
dc.contributor.author | Caldwell, Patrina Ha Yuen | |
dc.contributor.author | Sureshkumar, P | |
dc.contributor.author | Kerr, MI | |
dc.contributor.author | Hamilton, S | |
dc.contributor.author | Teixeira-Pinto, A | |
dc.contributor.author | Macaskill, P | |
dc.contributor.author | Craig, JC | |
dc.date.accessioned | 2016-04-15 | |
dc.date.available | 2016-04-15 | |
dc.date.issued | 2016-04-15 | |
dc.identifier.uri | http://hdl.handle.net/2123/14709 | |
dc.description.abstract | Objective: To compare a novel code-word alarm with a commercially available wireless alarm for treating enuresis Design: Randomised controlled trial with blinding of study personnel and outcome assessors Setting: A tertiary paediatric centre Patients: Children aged six to eighteen with at least three wet nights per week in the previous 6 months referred by doctors Outcomes: Primary outcome: the proportion who achieved a full response (14 consecutive dry nights) by 16 weeks. Secondary outcomes: change in frequency of wetting, duration of alarm training, percentage of wet nights that the child woke to the alarm, adherence to treatment, adverse events and satisfaction with treatment. Results: Of the 353 participants, 176 were assigned to the code-word alarm and 177 to control. At 16 weeks, 54% (95% CI, 47% to 61%) in the experimental group and 47% (95% CI, 40% to 55%) in the control group had achieved a full response (p=0.22), with 74% and 66% respectively attaining a 50% or more reduction in wetting frequency (p=0.14). The experimental group woke more often than the control group (median percentage of waking 88% versus 77%, p=0.003) and had greater reduction in wet nights (median reduction 10 versus 9 nights per fortnight). Fewer in the experimental group discontinued therapy before achieving a full response (27% versus 37% discontinued, p=0.04). There were no significant differences in relapse rates at 6 months, adverse events or satisfaction between the two alarms. In a post hoc subgroup analysis of children with monosymptomatic enuresis, more in the experimental group achieved a full response (66% versus 52%, p=0.047), with higher median percentage of waking (89% versus 79%, p=0.006) and greater reduction in wet nights (median reduction 12 versus 9 nights per fortnight). Conclusions: Although the code-word alarm increased waking, no difference in full response rates was demonstrated between the two alarms. | en_AU |
dc.description.sponsorship | The study was funded by an NHMRC Project Grant (570761). AT was supported by an NHMRC Program Grant (633003) to the Screening & Test Evaluation Program. | en_AU |
dc.language.iso | en_AU | en_AU |
dc.relation | NHMRC Project Grant. 570761 | en_AU |
dc.subject | enuresis | en_AU |
dc.subject | nocturnal enuresis | en_AU |
dc.subject | arousal | en_AU |
dc.subject | behaviour control | en_AU |
dc.title | A randomised controlled trial of a code-word enuresis alarm | en_AU |
dc.type | Article | en_AU |
dc.subject.asrc | FoR::111403 - Paediatrics | en_AU |
dc.identifier.doi | 101:326-331. http://hdl.handle.net/2123/14589 | |
dc.type.pubtype | Post-print | en_AU |
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