Browsing Sydney School of Public Health by subject "1112 Oncology and Carcinogenesis"
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16 The burden of cancer overdiagnosis in Australia
Published 2019Burden of cancer is increasing worldwide, and in Australia, partly due to overdiagnosis: cancers which would never cause symptoms or harm if left undetected. We sought to estimate the current burden of overdiagnosis of ...Presentation -
48 Trends in stage-specific breast cancer incidence in new south wales, australia: insights from 25 years of screening mammography
Published 2018Screening mammography aims to improve breast cancer (BC) prognosis by increasing the incidence of early-stage tumours in order to decrease the incidence of late-stage cancer, but no reports have investigated these potential ...Conference paper -
69 Impact of full-field digital mammography versus film-screen mammography: systematic review
Published 2018Most breast screening programs worldwide have replaced screen-film mammography (SFM) with full-field digital mammography (FFDM) in expectation of technical, clinical and economic advantages. However, we are only just now ...Presentation -
81 Has the transition to digital mammography in breast cancer screening resulted in real benefits?
Published 2019Most breast screening programmes worldwide have replaced Screen-Film mammography (SFM) with Full-field Digital Mammography (FFDM). While FFDM provides significant technical and practical advantages over SFM in the provision ...Presentation -
Accuracy and reading time for six strategies using digital breast tomosynthesis in women with mammographically negative dense breasts
Published 2017The objective of this study was to compare six strategies using digital breast tomosynthesis in women with mammographically negative dense breasts. This is a substudy of the ‘ASTOUND’ trial. 163 women who underwent ...Article -
Active surveillance as a management option for cervical intraepithelial neoplasia 2: An online experimental study
Published 2021The objective of this study was to investigate framing of active surveillance as a management option for cervical intraepithelial neoplasia (CIN)2 in women of childbearing age. We conducted a between-subjects factorial ...Open AccessArticle -
Adherence to prescribing restrictions for HER2-positive metastatic breast cancer in Australia: A national population-based observational study (2001-2016)
Published 2018Targeted cancer therapy is often complex, involving multiple agents and chemotherapeutic partners. In Australia, prescribing restrictions are put in place to reflect existing evidence of cost-effectiveness of these medicines. ...Open AccessArticle -
Adjunct Screening With Tomosynthesis or Ultrasound in Women With Mammography-Negative Dense Breasts: Interim Report of a Prospective Comparative Trial
Published 2016Purpose Debate on adjunct screening in women with dense breasts has followed legislation requiring that women be informed about their mammographic density and related adjunct imaging. Ultrasound or tomosynthesis can detect ...Open AccessArticle -
Agreement between digital breast tomosynthesis and pathologic tumour size for staging breast cancer, and comparison with standard mammography.
Published 2019Purpose: Tomosynthesis is proposed to improve breast cancer assessment and staging. We compared tomosynthesis and mammography in estimating the size of newly-diagnosed breast cancers. Methods: All pathologically-confirmed ...Article -
Artificial Intelligence (AI) for the early detection of breast cancer: a scoping review to assess AI’s potential for screening practice.
Published 2019Various factors are driving interest in the application of artificial intelligence (AI) for breast cancer (BC) detection, but it is unclear whether the evidence warrants large-scale use in population-based screening. We ...Article -
Artificial intelligence for breast cancer screening: Opportunity or hype?
Published 2017Interpretation of mammography for breast cancer (BC) screening can confer a mortality benefit through early BC detection, can miss a cancer that is present or fast growing, or can result in false-positives. Efforts to ...Article -
Assessing the efficacy of cancer screening
Published 2017© 2017 Jacklyn et al. Background: Population-based cancer screening has been established for several types of cancer in Australia and internationally. Screening may perform differently in practice from randomised controlled ...Open AccessArticle -
Assessing the Potential for Patient-led Surveillance After Treatment of Localized Melanoma (MEL-SELF) A Pilot Randomized Clinical Trial
Published 2022Patient-led surveillance is a promising new model of follow-up care following excision of localized melanoma. Objective To determine whether patient-led surveillance in patients with prior localized primary cutaneous ...Open AccessArticle -
The Association of Surgical Margins and Local Recurrence in Women with Ductal Carcinoma In Situ Treated with Breast-Conserving Therapy: A Meta-Analysis.
Published 2016Purpose: There is no consensus on adequate negative margins in breast-conserving surgery (BCS) for ductal carcinoma in situ (DCIS). We systematically reviewed the evidence on margins in BCS for DCIS. Methods: A study-level ...Article -
Beyond country‐specific incidence and mortality: the global burden of melanoma
Published 2018Editorial piece. In the July 2017 issue of the BJD, Karimkhani and colleagues reported on the Global Burden of Disease (GBD) Study 2015 melanoma results. The GBD uses a standardized statistical framework to analyse both ...Article, Letter -
Breast Cancer
Published 2019Breast cancer is the most frequent malignancy in women worldwide and is curable in ~70–80% of patients with early-stage, non-metastatic disease. Advanced breast cancer with distant organ metastases is considered incurable ...Article -
Breast cancer detection using single-reading of breast tomosynthesis (3D-mammography) compared to double-reading of 2D-mammography: Evidence from a population-based trial.
Published 2017Most population breast cancer (BC) screening programs use double-reading of 2D-mammography. We recently reported the screening with tomosynthesis or standard mammography-2 (STORM-2) trial, showing that double-read tomosynthesis ...Open AccessArticle -
Breast cancer Ki-67 expression prediction by digital breast tomosynthesis radiomics features
Published 2019The aim of this paper was to investigate whether quantitative radiomic features extracted from digital breast tomosynthesis (DBT) are associated with Ki-67 expression of breast cancer. This was a prospective ethically ...Open AccessArticle -
Breast Cancer Screening Using Tomosynthesis or Mammography: A Meta-analysis of Cancer Detection and Recall.
Published 2018Tomosynthesis approximates a 3D mammogram of the breast, reducing parenchymal overlap that masks cancers or creates false "lesions" on 2D mammography, and potentially enabling more accurate detection of breast cancer. We ...Article -
Breast cancer screening with tomosynthesis (3D mammography) with acquired or synthetic 2D mammography compared with 2D mammography alone (STORM-2): a population-based prospective study.
Published 2016Breast tomosynthesis (pseudo-3D mammography) improves breast cancer detection when added to 2D mammography. In this study, we examined whether integrating 3D mammography with either standard 2D mammography acquisitions or ...Article