• Acridinone-based anion transporters 

      McNaughton, Daniel A.; Macreadie, Lauren K.; Gale, Philip A.
      Published 2021
      The arrangement of hydrogen bond donors around a central lipophilic scaffold has proven a successful strategy in the development of potent chloride transporters. In this work, we revisit an acridinone 1,9-bis(thio)urea ...
      Open Access
      Article
    • Halide-selective, proton-coupled anion transport by phenylthiosemicarbazones 

      Howe, Ethan N.W.; Chang, Vai-Vai Tiffany; Wu, Xin; Fares, Mohamed; Lewis, William; Macreadie, Lauren K.; Gale, Philip A.
      Published 2022
      Phenylthiosemicarbazones (PTSCs) are proton-coupled anion transporters with pH-switchable behaviour known to be regulated by an imine protonation equilibrium. Previously, chloride/nitrate exchange by PTSCs was found to be ...
      Open Access
      Article
    • Tetrapodal Anion Transporters 

      Gilchrist, Alexander M.; Chen, Lijun; Wu, Xin; Lewis, William; Howe, Ethan N.W.; Macreadie, Lauren K.; Gale, Philip A.
      Published 2020-01-01
      Synthetic anion transporters that facilitate chloride transport are promising candidates for channelopathy treatments. However, most anion transporters exhibit an undesired side effect of facilitating proton transport via ...
      Open Access
      Article