Browsing by author "Chan, Bun"
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Accelerated Protein Synthesis via One-Pot Ligation-Deselenization Chemistry
Mitchell, Nicholas J.; Sayers, Jessica; Kulkarni, Sameer S.; Clayton, Daniel; Goldys, Anna M.; Ripoll-Rozada, Jorge; Pereira, Pedro Jose Barbosa; Chan, Bun; Radom, Leo; Payne, Richard J.Published 2017-05-11Peptide ligation chemistry has revolutionized protein science by facilitating access to synthetic proteins. Here, we describe the development of additive-free ligation-deselenization chemistry at β-selenoaspartate and ...Open AccessArticle -
Chemoselective Peptide Ligation–Desulfurization Chemistry at Aspartate
Thompson, Robert E.; Chan, Bun; Radom, Leo; Jolliffe, Katrina A.; Payne, Richard J.Published 2013-07-24Asp‐ecially useful : A synthetic β‐mercapto aspartate residue facilitates the rapid ligation to a range of peptide thioesters. Following the ligation reaction (and without purification), chemoselective desulfurization of ...Open AccessArticle -
Construction of Challenging Proline−Proline Junctions via 2 Diselenide−Selenoester Ligation Chemistry
Sayers, Jessica; Karpati, Phillip M. T.; Mitchell, Nicholas J.; Goldys, Anna M.; Kwong, Stephen M.; Firth, Neville; Chan, Bun; Payne, Richard J.Published 2018-09-21Polyproline sequences are highly abundant in prokaryotic and eukaryotic proteins, where they serve as key components of secondary structure. To date, construction of the proline–proline motif has not been possible owing ...Open AccessArticle -
Fluorescence Enhancement through Confined Oligomerization in Nanochannels: An Anthryl Oligomer in a Metal-Organic Framework
Wang, Tiesheng; Sabatini, Randy P.; Chan, Bun; Hou, Jingwei; Huynh, Vien T.; Proschogo, Nicholas; Xie, Zixi; Wang, Tan; Gao, Long; Zhang, Jiaqi; Hawkett, Brian S.; Clarke, Ronald J.; Kepert, Cameron J.; Chen, Vicki; Lakhwani, Girish; D’Alessandro, Deanna M.Published 2021Nanoconfinement offers opportunities to tune physical properties of molecular entities by altering their assembled structures. This also applies to acene-based molecules with potentially rich π–π interactions. Unlike most ...Open AccessPreprint -
Increasing spin crossover cooperativity in 2D Hofmann-type materials with guest molecule removal
Zenere, Katrina A.; Duyker, Samuel G.; Trzop, Elzbieta; Collet, Eric; Chan, Bun; Doheny, Patrick W.; Kepert, Cameron J.; Neville, Suzanne M.Published 2018-01-01Molecule-based spin state switching materials that display ambient temperature transitions with accompanying wide thermal hysteresis offer an opportunity for electronic switching, data storage, and optical technologies but ...Article -
Rapid Additive-Free Selenocystine–Selenoester Peptide Ligation
Mitchell, Nicholas J.; Malins, Lara R.; Liu, Xuyu; Thompson, Robert E.; Chan, Bun; Radom, Leo; Payne, Richard J.Published 2015-10-21We describe an unprecedented reaction between peptide selenoesters and peptide dimers bearing N-terminal selenocystine that proceeds in aqueous buffer to afford native amide bonds without the use of additives. The ...Open AccessArticle
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