Research Publications and Outputs: Recent submissions
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What’s the uptake? Pragmatic RCTs may be used to estimate uptake, and thereby population impact of interventions, but better reporting of trial recruitment processes is needed
Published 2017Effectiveness of interventions in pragmatic trials may not translate directly into population impact, because of limited uptake by clinicians and/or the public. Uptake of an intervention is influenced by a number of ...Open AccessArticle -
96 Can we detect overdiagnosis early? exploring indicators of possible overdiagnosis outside cancer screening contexts
Published 2018Although the risk of overdiagnosis in cancer screening was identified almost 50 years ago, evidence of cancer overdiagnosis was slow to emerge, and has required development of new approaches and study designs. As a result, ...Conference paper -
89 Incremental benefits and harms of the 2017 american college of cardiology/american heart association high blood pressure guideline
Published 2018The recent recommendations from the American College of Cardiology and the American Heart Association (ACC/AHA) to lower the thresholds for defining hypertension follows a general pattern across medical specialties, whereby ...Conference paper -
Systematic review of the effects of care provided with and without diagnostic clinical prediction rules
Published 2017Diagnostic clinical prediction rules (CPRs) are worthwhile if they improve patient outcomes or provide benefits such as reduced resource use, without harming patients. We conducted a systematic review to assess the effects ...Open AccessArticle -
Early CRT monitoring using time-domain optical coherence tomography does not add to visual acuity for predicting visual loss in patients with central retinal vein occlusion treated with intravitreal Ranibizumab
Published 2017Our primary purpose was to assess the clinical (predictive) validity of central retinal thickness (CRT) and best corrected visual acuity (BCVA) at 1 week and 1 month after starting treatment with ranibizumab for central ...Open AccessArticle