Browsing Research Publications and Outputs by subject "1102 Cardiorespiratory Medicine and Haematology"
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23 Heart age: intuitive communication tool or gateway to overdiagnosis? A comparison of 3 countries
Published 2019Heart age calculators are increasingly popular around the world as a way to promote and communicate cardiovascular disease (CVD) risk assessment to patients/consumers. While they have intuitive appeal, the implicit assumptions ...Presentation -
89 Incremental benefits and harms of the 2017 american college of cardiology/american heart association high blood pressure guideline
Published 2018The recent recommendations from the American College of Cardiology and the American Heart Association (ACC/AHA) to lower the thresholds for defining hypertension follows a general pattern across medical specialties, whereby ...Conference paper -
A Counterargument to Encounter Frequency and Target Achievement: Measurement Variability
Published 2012Editorial response to the conclusion of the recent report by Morrison and colleagues that encounter frequency leads to apparent better control of glucose (hemoglobin A1c), blood pressure, and low-density lipoprotein ...Article, Letter -
Decision Support Tools for Coronary Artery Calcium Scoring in the Primary Prevention of Cardiovascular Disease Do Not Meet Health Literacy Needs: A Systematic Environmental Scan and Evaluation
Published 2022A shared decision-making approach is considered optimal in primary cardiovascular disease (CVD) prevention. Evidence-based patient decision aids can facilitate this but do not always meet patients’ health literacy needs. ...Open AccessArticle -
Effects of additional blood pressure and lipid measurements on the prediction of cardiovascular risk
Published 2012Current guidelines recommend that decisions to start preventative therapy for cardiovascular disease (CVD) should be based on absolute risk; however, current risk equations are based on single measurements of risk factors. ...Article -
Estimated legacy effects from simulated post-trial data were less biased than from combined trial/post-trial data.
Published 2019“Legacy effects” describe the phenomena where treatment effects are apparent during the post-trial period that are not attributable to the direct effects observed within the trial. We investigate different approaches to ...Open AccessArticle -
Evaluation of the Incremental Value of a Coronary Artery Calcium Score Beyond Traditional Cardiovascular Risk Assessment A Systematic Review and Meta-analysis
Published 2022Coronary artery calcium scores (CACS) are used to help assess patients’ cardiovascular status and risk. However, their best use in risk assessment beyond traditional cardiovascular factors in primary prevention is ...Open AccessArticle -
Future directions in cardiovascular disease risk prediction.
Published 2020Although the National Vascular Disease Prevention Alliance (NVDPA) guidelines were published in 2012, many individuals at high risk of cardiovascular disease (CVD) are not prescribed preventive medication or have CVD risk ...Article -
The impact of health literacy on psychosocial and behavioural outcomes among people at low risk of cardiovascular disease
Published 2022This study aimed to explore the impact of health literacy on psychosocial and behavioural outcomes for people who were not at high risk of cardiovascular disease receiving a hypothetical blood pressure reading of 135/85 ...Article -
Incremental benefits and harms of the 2017 American College of Cardiology/American Heart Association high blood pressure guideline.
Published 2018The recent recommendations from the American College of Cardiology and the American Heart Association (ACC/AHA) to lower the thresholds for defining hypertension and for treating higher-risk patients1 have been controversial. ...Article -
Is the NHS ‘Heart Age Test’ too much medicine?
Published 2019The NHS ‘Heart Age Test’has expanded cardiovascular disease (CVD) risk assessment in the UK to include younger people (< 40 years). Public Health England’s (PHE) Healthy Heart campaign, launched in September 2018, encourages ...Article -
Legacy effect of fibrate add-on therapy in diabetic patients with dyslipidemia: a secondary analysis of the ACCORDION study.
Published 2020The Action to Control Cardiovascular Risk in Diabetes (ACCORD)-Lipid study found no evidence of a beneficial effect of statin-fibrate combined treatment, compared to statins alone, on cardiovascular outcomes and mortality ...Open AccessArticle -
Mendelian Randomization in Cardiovascular Research: Establishing Causality When There Are Unmeasured Confounders
Published 2021Mendelian randomization is an epidemiological approach to making causal inferences using observational data. It makes use of the natural randomization that occurs in the generation of an individual’s genetic makeup in a ...Article -
A methods review of posttrial follow-up studies of cardiovascular prevention finds potential biases in estimating legacy effects
Published 2020The objective of the study was to assess the methods used, and potential for bias, in posttrial studies of cardiovascular disease (CVD) where legacy effects may be estimated. We undertook a methods review of posttrial ...Open AccessArticle -
Mixed models showed no need for initial response monitoring after starting antihypertensive therapy.
Published 2009The objective of this study was to demonstrate how mixed models may be used to estimate treatment effects, and inform decisions on the need for monitoring initial response. Mixed models were used to analyze data from ...Open AccessArticle -
Monitoring adherence to drug treatment by using change in cholesterol concentration: secondary analysis of trial data.
Published 2011A randomised controlled trial which aimed to estimate the accuracy of monitoring cholesterol concentration for detecting non-adherence to lipid lowering treatment. Design: Secondary analysis of data on cholesterol ...Article -
Monitoring Adherence to Medication by Measuring Change in Blood Pressure.
Published 2010After starting antihypertensives, blood pressure is monitored for several reasons, including assessment of adherence. We aimed to estimate the accuracy of blood pressure monitoring for detecting early nonadherence. We ...Open AccessArticle -
[OP.1C.01] Increased Blood Pressure Variability predicts all-cause mortality in patients with diabetes free of cardiovascular disease and not on antihypertensive drugs.
Published 2017Blood pressure variability has been associated with risk of cardiovascular events in observational studies, independently of mean blood pressure (BP) levels. BP variability is typically summarized as the standard deviation ...Open AccessConference paper -
Patterns and trends of potentially inappropriate high-density lipoprotein cholesterol testing in Australian adults at high risk of cardiovascular disease from 2008 to 2014: analysis of linked individual patient data from the Australian Medicare Benefits Schedule and Pharmaceutical Benefits Scheme.
Published 2018Objectives We examine the extent to which the adult Australian population on lipid-lowering medications receives the level of high-density lipoprotein cholesterol (HDL-C) testing recommended by national guidelines. Data ...Open AccessArticle -
The potential for overdiagnosis and underdiagnosis because of blood pressure variability: a comparison of the 2017 ACC/AHA, 2018 ESC/ESH and 2019 NICE hypertension guidelines.
Published 2021The objective of this paper was to estimate the extent that BP measurement variability may drive over- and underdiagnosis of ‘hypertension’ when measurements are made according to current guidelines. Using data from the ...Open AccessArticle