Browsing Research Publications and Outputs by subject "0299 Other Physical Sciences"
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The Accuracy and Precision of the KIM Motion Monitoring System Used in the Multi-Institutional TROG 15.01 Stereotactic Prostate Ablative Radiotherapy With KIM (SPARK) Trial
Published 2019-01-01Purpose: Kilovoltage intrafraction monitoring (KIM) allows for real-time image guidance for tracking tumor motion in six-degrees-of-freedom (6DoF) on a standard linear accelerator. This study assessed the geometric accuracy ...Open AccessArticle -
Anatomical Deformation Due to Horizontal Rotation: Towards Gantry-Free Radiation Therapy
Published 2019-01-01Gantry-free radiation therapy systems may be simpler and more cost effective, particularly for MRI-guided photon or hadron therapy. This study aims to understand and quantify anatomical deformations caused by horizontal ...Open AccessArticle -
Dosimetric impact of intrafraction rotations in stereotactic prostate radiotherapy: A subset analysis of the TROG 15.01 SPARK trial.
Published 2019-01-01Background and purpose: Accurate delivery of radiotherapy is critical to achieve optimal treatment outcomes. Interfraction translational IGRT is now standard, and intrafraction motion management is becoming accessible. ...Open AccessArticle -
Dual cardiac and respiratory gated thoracic imaging via adaptive gantry velocity and projection rate modulation on a linear accelerator: A Proof-of-Concept Simulation Study.
Published 2019-01-01Purpose: Cardiac motion is typically not accounted for during pretreatment imaging for central lung and mediastinal tumors. However, cardiac induced tumor motion averages 5.8 mm for esophageal tumors and 3-5 mm for some ...Open AccessArticle -
Evaluating reconstruction algorithms for respiratory motion guided acquisition
Published 2020Conventional thoracic 4DCBCT scans take 1320 projections over 4 min. This paper investigates which reconstruction algorithms best leverage Respiratory-Motion-Guided (RMG) acquisition in order to reduce scan time and dose ...Open AccessArticle -
FLASH radiotherapy: Newsflash or flash in the pan?
Published 2019-01-01No abstract. A point / counterpoint article on the merits of ultra-high dose rate radiation therapy.Open AccessArticle -
Imaging of regional ventilation: Is CT ventilation imaging the answer? A systematic review of the validation data.
Published 2019-01-01Computed Tomography Ventilation Imaging (CTVI) is an experimental imaging modality that derives regional lung function information from non-contrast respiratory-correlated CT datasets. Despite CTVI being extensively studied ...Open AccessArticle -
Real-time direct diaphragm tracking using kV imaging on a standard linear accelerator.
Published 2019-01-01Purpose: As the predominant driver of respiratory motion, the diaphragm represents a key surrogate for motion management during the irradiation of thoracic cancers. Existing approaches to diaphragm tracking often produce ...Open AccessArticle -
Real-Time Image Guided Ablative Prostate Cancer Radiation Therapy: Results From the TROG 15.01 SPARK Trial
Published 2020Purpose: Kilovoltage intrafraction monitoring (KIM) is a novel software platform implemented on standard radiation therapy systems and enabling real-time image guided radiation therapy (IGRT). In a multi-institutional ...Open AccessArticle -
Reducing 4D CT imaging artifacts at the source: first experimental results from the respiratory adaptive computed tomography (REACT) system
Published 2020Breathing variations during 4D CT imaging often manifest as geometric irregularities known as respiratory-induced image artifacts and ultimately effect radiotherapy treatment efficacy. To reduce such image artifacts we ...Open AccessArticle -
See, Think, and Act: Real-Time Adaptive Radiotherapy.
Published 2019-01-01The world is embracing the information age, with real-time data at hand to assist with many decisions. Similarly, in cancer radiotherapy we are inexorably moving toward using information in a smarter and faster fashion, ...Open AccessArticle -
Simulated multileaf collimator tracking for stereotactic liver radiotherapy guided by kilovoltage intrafraction monitoring: Dosimetric gain and target overdose trends
Published 2020Purpose: To investigate the potential benefit of multileaf collimator (MLC) tracking guided by kilovoltage intrafraction monitoring (KIM) during stereotactic body radiotherapy (SBRT) in the liver, and to understand trends ...Open AccessArticle -
SPARE: Sparse-view reconstruction challenge for 4D cone-beam CT from a 1-min scan.
Published 2019-01-01Purpose: Currently, four-dimensional (4D) cone-beam computed tomography (CBCT) requires a 3-4 min full-fan scan to ensure usable image quality. Recent advancements in sparse-view 4D-CBCT reconstruction have opened the ...Open AccessArticle -
Technical Note: Experimental Characterization of the Dose Deposition in Parallel MRI-linacs at Various Magnetic Field Strengths
Published 2019-01-01Purpose: Dose deposition measurements for parallel MRI-linacs have previously only shown comparisons between 0 T and a single available magnetic field. The Australian MRI-Linac consists of a magnet coupled with a dual ...Open AccessArticle -
Technical Note: The first live treatment on a 1.0 Tesla inline MRI-linac.
Published 2019-01-01Purpose: This work describes the first live imaging and radiation delivery performed on a prototype 1.0 T inline MRI-Linac system in a rat brain tumor model, which was conducted on 29 January 2019. Methods: A human scale ...Open AccessArticle -
Time-resolved Volumetric MRI in MRI-guided Radiotherapy: An in Silico Comparative Analysis
Published 2019-01-01MRI-treatment units enable 2D cine-MRI centred in the tumour for motion detection in radiotherapy, but they lack 3D information due to spatio-temporal limits. To derive time-resolved 3D information, different approaches ...Open AccessArticle -
Toward improved 3D carotid artery imaging with Adaptive CaRdiac cOne BEAm computed Tomography (ACROBEAT)
Published 2020Purpose: Interventional treatments of aneurysms in the carotid artery are increasingly being supplemented with three-dimensional (3D) x-ray imaging. The 3D imaging provides additional information on device sizing and stent ...Open AccessArticle