Sydney Digital Theses (Open Access): Recent submissions
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Investigating the roles of dipeptidyl peptidase 9 (DPP9) in inflammation
Published 2024The DPP4 family members (DPP4, DPP8, DPP9 and FAP) are atypical enzymes that can cleave the post proline bond two residues from the N-terminus of a substrate. Inhibitors of the four proteases of the DPP4 family, which ...Open AccessThesis -
Mitochondrial and inflammatory biomarkers in patients with Parkinson's disease and REM sleep behaviour disorder
Published 2024Parkinson’s Disease (PD) pathologically defined by the accumulation of alpha-synuclein (α-syn) aggregates and selective loss of dopaminergic neurons is the most common neurodegenerative movement disorder and one of the ...Open AccessThesis -
Advancements in Variational Bayesian Computation: Theory and Applications in Hybrid and Particle-based Methods
Published 2024This thesis advances Variational Bayesian inference methods to address challenges in statistical models with complex structures, intractable likelihoods, and high-dimensional settings. Traditional Variational Bayes (VB) ...Open AccessThesis -
Investigating Adverse Drug Events and Adverse Drug Withdrawal Effects Associated with Heart Failure Pharmacotherapy in Older People Living with Frailty
Published 2025Background Frailty is common among older people with heart failure (HF). Optimising HF medications can improve clinical outcomes, but efficacy and safety are uncertain for older people with frailty. Aim To explore ...Open AccessThesis -
The Human Right to Higher Education in Principle and Practice: Public Policy Approaches to Facilitate University Participation in Australia and Sri Lanka, 1945-2015
Published 2024This thesis explores the notion of a human right to higher education (HRHE) as it is articulated under public international law, and examines progress towards its realisation in Australia and Sri Lanka, focusing on university ...Open AccessThesis