Sydney Digital Theses (Open Access): Recent submissions
-
In vitro time-kill studies and in vivo efficacy of phage and antibiotic treatments against respiratory Pseudomonas aeruginosa infection
Published 2024Phage and antibiotic combination therapy is a promising approach for treating pulmonary infections caused by multidrug-resistant Pseudomonas aeruginosa, a major pathogen in conditions like cystic fibrosis, bronchiectasis ...Open AccessThesis -
Validation of novel non-invasive diagnostic and prognostic methods in chronic kidney disease and kidney transplantation
Published 2025There is an emerging need to accurately detect chronic kidney disease (CKD) at an early stage so timely intervention can be implemented to optimize clinical outcomes. There remains a critical unmet requirement to develop ...EmbargoedThesis -
The Development of a Multifactorial Mouse Model of Maternal Immune Activation for study of Neurodevelopmental Disorders
Published 2025Neurodevelopmental disorders (NDDs) like autism, Tourette’s, ADHD, and intellectual disability are rising globally and typically emerge in early childhood. Their origins reflect complex gene–environment interactions during ...Open AccessThesis -
Application of bacteriophages as a biocontrol strategy for Rhodococcus equi in the soil of horse breeding farms
Published 2025R. equi is a soil saprophyte responsible for bronchopneumonia in young foals. The absence of a vaccine and the rise of multidrug-resistant strains necessitate alternative strategies for managing R. equi and mitigating ...Open AccessThesis -
Targeting regulators of lipogenesis in drug-tolerant persister cells
Published 2025Glioblastoma is a fatal brain tumour, with a median survival of less than 15 months. There has been no change to the standard-of-care since 2005. CMPD1 is a small-molecule microtubule-targeting agent with a cytotoxic ...Open AccessThesis