Sydney Digital Theses (Open Access): Recent submissions
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Characterising senescence in iPSC-derived glial cells from amyotrophic lateral sclerosis patients expressing the C9orf72 mutation.
Published 2024ALS is a motor neuron disease characteristic of upper and lower motor neuron degeneration, with limited treatment options and no cure. Senescence, a stress state cells enter in response to DNA damage, has recently been ...Open AccessThesis -
Investigating the mechanism of action of the chemical probe QC6352
Published 2024Glioblastoma, despite being the most aggressive form of brain cancer, has seen no significant advancement in patient survival rates since the introduction of the Stupp protocol in 2005. The stagnation in therapeutic progress ...Open AccessThesis -
The development of long-term normothermic machine perfusion in liver transplantation: assessment of organ quality and viability, and an exploration of barriers to clinical practice
Published 2024Various machine perfusion techniques utilised in liver transplantation have established advantages when applied clinically in the short term. However, if perfusion could be safely extended beyond hours, to days or even ...Open AccessThesis -
Research on Space-based 3D Printing
Published 2023Space-based manufacturing technology provides a promising solution for deep space exploration and long-term space missions. The distinguished merits of 3d printing include complex geometry fabrication, minimum material ...Open AccessThesis -
Measuring Fiscal Stance in Australia: Theoretical, Empirical and Policy Considerations
Published 2003Cyclical volatility in the rate of economic growth has been a source of concern for economic policy makers since the Keynesian revolution changed governments’ perception of their role in macroeconomic management. While ...Open AccessThesis