Browsing The Daffodil Centre by author "Aitken JF"
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BRCA2 mutations in a population-based series of patients with ocular melanoma
Scott RJ; Vajdic CM; Armstrong BK; Ainsworth CJ; Meldrum CJ; Aitken JF; Kricker APublished 2002We studied the BRCA2 gene for germline mutations in 71 of 99 patients (72%) with ocular melanoma who were diagnosed consecutively in Australia in 1997 and 1998. Patients considered for our study fulfilled one of the following ...Article -
Chromosomal gains and losses in ocular melanoma detected by comparative genomic hybridization in an Australian population-based study
Vajdic CM; Hutchins AM; Kricker A; Aitken JF; Armstrong BK; Hayward NK; Armes JEPublished 2003To define the location of potential oncogenes and tumor suppressor genes in ocular melanoma we carried out comparative genomic hybridization (CGH) analysis on a population-based series of 25 formalin-fixed, paraffin-embedded ...Article -
Ocular melanoma is not associated with CDKN2A or MC1R variants--a population-based study
Vajdic C; Kricker A; Duffy DL; Aitken JF; Stark M; ter Huurne JA; Martin NG; Armstrong BK; Hayward NKPublished 2003Germline variants in the melanocortin 1 receptor gene (MC1R) and the p16 gene (CDKN2A) are associated with an increased risk of cutaneous melanoma. The frequency of these germline variants was examined in a population-based, ...Article
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