Adjunct Screening With Tomosynthesis or Ultrasound in Women With Mammography-Negative Dense Breasts: Interim Report of a Prospective Comparative Trial
Field | Value | Language |
dc.contributor.author | Tagliafico, Alberto S | |
dc.contributor.author | Calabrese, Massimo | |
dc.contributor.author | Mariscotti, Giovanna | |
dc.contributor.author | Durando, Manuela | |
dc.contributor.author | Tosto, Simona | |
dc.contributor.author | Monetti, Francesco | |
dc.contributor.author | Airalda, Sonia | |
dc.contributor.author | Bignotti, Bianca | |
dc.contributor.author | Nori, Jacopo | |
dc.contributor.author | Bagni, Antonella | |
dc.contributor.author | Signori, Alessio | |
dc.contributor.author | Sormani, Maria Pia | |
dc.contributor.author | Houssami, Nehmat | |
dc.date.accessioned | 2021-11-25T22:28:06Z | |
dc.date.available | 2021-11-25T22:28:06Z | |
dc.date.issued | 2016 | en_AU |
dc.identifier.uri | https://hdl.handle.net/2123/26959 | |
dc.description.abstract | Purpose Debate on adjunct screening in women with dense breasts has followed legislation requiring that women be informed about their mammographic density and related adjunct imaging. Ultrasound or tomosynthesis can detect breast cancer (BC) in mammography-negative dense breasts, but these modalities have not been directly compared in prospective trials. We conducted a trial of adjunct screening to compare, within the same participants, incremental BC detection by tomosynthesis and ultrasound in mammography-negative dense breasts. Patients and Methods Adjunct Screening With Tomosynthesis or Ultrasound in Women With Mammography-Negative Dense Breasts is a prospective multicenter study recruiting asymptomatic women with mammography-negative screens and dense breasts. Eligible women had tomosynthesis and physician-performed ultrasound with independent interpretation of adjunct imaging. Outcome measures included cancer detection rate (CDR), number of false-positive (FP) recalls, and incremental CDR for each modality; these were compared using McNemar’s test for paired binary data in a preplanned interim analysis. | en_AU |
dc.language.iso | en | en_AU |
dc.publisher | American Society of Clinical Oncology | en_AU |
dc.relation.ispartof | Journal of Clinical Oncology | en_AU |
dc.rights | Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 | en_AU |
dc.subject | Tomosynthesis | en_AU |
dc.subject | Mammography | en_AU |
dc.subject | Breast density | en_AU |
dc.subject | Adjunct screening | en_AU |
dc.subject | Ultrasound | en_AU |
dc.title | Adjunct Screening With Tomosynthesis or Ultrasound in Women With Mammography-Negative Dense Breasts: Interim Report of a Prospective Comparative Trial | en_AU |
dc.type | Article | en_AU |
dc.subject.asrc | 1112 Oncology and Carcinogenesis | en_AU |
dc.subject.asrc | 1117 Public Health and Health Services | en_AU |
dc.identifier.doi | 10.1200/JCO.2015.63.4147 | |
dc.relation.other | Associazione Italiana per la Ricerca sul Cancro (IG n.15697) | |
dc.relation.other | University of Genoa (PRA 2013) | |
dc.relation.other | National Breast Cancer Foundation Australia Breast Cancer Research Leadership Fellowship | |
usyd.faculty | SeS faculties schools::Faculty of Medicine and Health::Sydney School of Public Health | en_AU |
usyd.citation.volume | 34 | en_AU |
usyd.citation.issue | 16 | en_AU |
usyd.citation.spage | 1882 | en_AU |
usyd.citation.epage | 1890 | en_AU |
workflow.metadata.only | No | en_AU |
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