Genetic basis of O-antigen variation in Salmonella spp.: rfb gene clusters of S. typhi and S. paratyphi A
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Type
ThesisThesis type
Doctor of PhilosophyAuthor/s
Verma, Naresh K.Abstract
The O—antigens of Salmonella serogroups A, B and D differ structurally in their side-chain sugar residue. The genes encoding 0antigen biosynthesis are clustered in the rfb operon. This thesis describes the molecular cloning and analysis of the rfb genes from S. paratyphi A IMVSl316 ...
See moreThe O—antigens of Salmonella serogroups A, B and D differ structurally in their side-chain sugar residue. The genes encoding 0antigen biosynthesis are clustered in the rfb operon. This thesis describes the molecular cloning and analysis of the rfb genes from S. paratyphi A IMVSl316 (serogroup A) and S. typhi Ty21a (serogroup D). The rfb gene cluster from S. Typhimurium LT2 (serogroup B) has also been studied in our laboratory (Brahmbhatt et al 1986, 1988; P. Wyk, Ph.D. thesis, Univ. of Adelaide, 1988). The genetic basis of O-antigen variation in serogroups A, B and D of Salmonella is dscussed.
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See moreThe O—antigens of Salmonella serogroups A, B and D differ structurally in their side-chain sugar residue. The genes encoding 0antigen biosynthesis are clustered in the rfb operon. This thesis describes the molecular cloning and analysis of the rfb genes from S. paratyphi A IMVSl316 (serogroup A) and S. typhi Ty21a (serogroup D). The rfb gene cluster from S. Typhimurium LT2 (serogroup B) has also been studied in our laboratory (Brahmbhatt et al 1986, 1988; P. Wyk, Ph.D. thesis, Univ. of Adelaide, 1988). The genetic basis of O-antigen variation in serogroups A, B and D of Salmonella is dscussed.
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Date
1988Licence
The author retains copyright of this thesisRights statement
The author retains copyright of this thesis. It may only be used for the purposes of research and study. It must not be used for any other purposes and may not be transmitted or shared with others without prior permission.Department, Discipline or Centre
Department of MicrobiologyAwarding institution
The University of SydneyShare