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dc.contributor.authorDaniels, Benjamin
dc.contributor.authorGirosi, Federico
dc.contributor.authorTervonen, Hanna
dc.contributor.authorKiely, Belinda E
dc.contributor.authorLord, Sally J
dc.contributor.authorHoussami, Nehmat
dc.contributor.authorPearson, Sallie-Anne
dc.date.accessioned2021-09-08T05:33:24Z
dc.date.available2021-09-08T05:33:24Z
dc.date.issued2018en_AU
dc.identifier.urihttps://hdl.handle.net/2123/25957
dc.description.abstractTargeted cancer therapy is often complex, involving multiple agents and chemotherapeutic partners. In Australia, prescribing restrictions are put in place to reflect existing evidence of cost-effectiveness of these medicines. As therapeutic options continue to expand, these restrictions may not be perceived to align with best practice and it is not known if their use in the real-world clinic adheres to these restrictions. We examined the treatment of women receiving trastuzumab for HER2-positive metastatic breast cancer (HER2+MBC) to determine the extent to which treatment adhered to national prescribing restrictions.en_AU
dc.language.isoenen_AU
dc.publisherPublic Library of Scienceen_AU
dc.relation.ispartofPLoS ONEen_AU
dc.rightsCreative Commons Attribution 4.0en_AU
dc.subjectcancer treatmenten_AU
dc.subjectchemotherapyen_AU
dc.subjectcombination chemotherapyen_AU
dc.subjectchemotherapeutic agentsen_AU
dc.subjectoncologyen_AU
dc.subjectbreast canceren_AU
dc.subjectmetastasisen_AU
dc.titleAdherence to prescribing restrictions for HER2-positive metastatic breast cancer in Australia: A national population-based observational study (2001-2016)en_AU
dc.typeArticleen_AU
dc.subject.asrc1112 Oncology and Carcinogenesisen_AU
dc.subject.asrc1117 Public Health and Health Servicesen_AU
dc.identifier.doi10.1371/journal.pone.0198152
dc.relation.nhmrc1060407
dc.relation.nhmrc1094325
dc.relation.othera Cancer Australia Priority Driven Collaborative Support Scheme (ID: 1050648)
usyd.facultySeS faculties schools::Faculty of Medicine and Health::Sydney School of Public Healthen_AU
usyd.citation.volume13en_AU
usyd.citation.issue7en_AU
workflow.metadata.onlyNoen_AU


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