Lesions of uncertain malignant potential of the breast (B3) on vacuum-assisted biopsy for microcalcifications: Predictors of malignancy
Type
ArticleAuthor/s
Mariscotti, GiovannaDurando, Manuela
Ruggirello, Irene
Calabrese, Massimo
Fonio, Paolo
Houssami, Nehmat
Belli, Paolo
Caumo, Francesca
Nori, Jacopo
Zuiani, Chiara
Tagliafico, Alberto
Bicchierai, Giulia
Romanucci, Giovanna
Londero, Viviana
Campanino, Pier Paolo
Bussone, Riccardo
Castellano, Isabella
Mule, Antonio
Caneva, Andrea
Bianchi, Simonetta
Di Loreto, Carla
Bergamasco, Laura
Abstract
To investigate clinical, radiologic and pathologic features of B3 lesions diagnosed on VABB targeting microcalcifications, for identifying predictors of malignancy.
This retrospective multi-centre study included consecutive VABBs performed over a 10-year period on suspicious ...
See moreTo investigate clinical, radiologic and pathologic features of B3 lesions diagnosed on VABB targeting microcalcifications, for identifying predictors of malignancy. This retrospective multi-centre study included consecutive VABBs performed over a 10-year period on suspicious microcalcifications not associated with other radiological signs diagnosed as B3 on histology from VABB, with outcomes ascertained by surgical excision. Clinical, demographic, radiological and histological (B3 subcategory) data were collected. For statistical analysis (univariate and binary logistic regression), the primary outcome variable was the upgrade rate to malignancy after surgery. Predictors of upgrade to malignancy were identified from clinical, demographic, radiological and pathological variables (including B3 subcategory).
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See moreTo investigate clinical, radiologic and pathologic features of B3 lesions diagnosed on VABB targeting microcalcifications, for identifying predictors of malignancy. This retrospective multi-centre study included consecutive VABBs performed over a 10-year period on suspicious microcalcifications not associated with other radiological signs diagnosed as B3 on histology from VABB, with outcomes ascertained by surgical excision. Clinical, demographic, radiological and histological (B3 subcategory) data were collected. For statistical analysis (univariate and binary logistic regression), the primary outcome variable was the upgrade rate to malignancy after surgery. Predictors of upgrade to malignancy were identified from clinical, demographic, radiological and pathological variables (including B3 subcategory).
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Date
2020Source title
European Journal of RadiologyVolume
130Publisher
ElsevierLicence
Copyright All Rights ReservedFaculty/School
Faculty of Medicine and Health, Sydney School of Public HealthShare