Theses: Recent submissions
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The Development of Novel Lung-Tropic AAVs to Support a Gene Therapy for Cystic Fibrosis
Published 2025Cystic fibrosis (CF) is a life-shortening disease that affects all mucosal surfaces of the body, with the more severe symptoms manifesting in the respiratory system. This monogenic disease is caused by a variety of mutations ...USyd AccessThesis -
Molecular Determinants of Treatment Response and Outcomes in Acute Myeloid Leukaemia with mutated NPM1
Published 2025Mutations in the nucleophosmin (NPM1) gene occur in ~30% of adult AML, where they define a distinct disease subtype associated with relatively favourable prognosis. Outcomes are impacted by age, mutations in FLT3-ITD and ...USyd AccessThesis -
Post-sentence detention and supervision in New South Wales: Constructing the subject as a high risk offender
Published 2025This Thesis examines the Terrorism (High Risk Offenders) Act 2017 (NSW) (THRO Act). The THRO Act constructs a post-sentence supervision and detention regime for people who are purported to pose an unacceptable risk of ...Open AccessThesis -
Prostate Specific Membrane Antigen as a Diagnostic and Therapeutic Target
Published 2025Prostate specific membrane antigen (PSMA) based imaging could improve clinical outcomes in men with metastatic castration resistant prostate cancer treated with 177Lutetium-PSMA-617. This thesis aimed to identify imaging ...Open AccessThesis -
Task Offloading and Resource Allocation for 5G and Beyond Networks
Published 2025In this thesis, we give a detailed analysis of the challenges encountered in the 5G and beyond networks in the field of resource allocation. To start with, we provide an introduction to the development of communication ...Open AccessThesis