Faculty of Medicine and Health: Recent submissions
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Evolving geographic diversity in SARS-CoV2 and in silico analysis of replicating enzyme 3CLpro targeting repurposed drug candidates
Published 2020Background: Severe acute respiratory syndrome (SARS) has been initiating pandemics since the beginning of the century. In December 2019, the world was hit again by a devastating SARS episode that has so far infected almost ...Article -
A narrative review of the safety concerns of deprescribing in older adults and strategies to mitigate potential harms
Published 2018-01-01Introduction: As with prescribing or continuing medications, deprescribing brings with it the potential for harm as well as benefit. Uncertainty and avoidance of harm has been reported as a barrier to deprescribing in ...Open AccessArticle -
Community-dwelling older people's attitudes towards deprescribing in Canada
Published 2017-01-01Background While there is evidence that supervised withdrawal of inappropriate medications might be beneficial for individuals with polypharmacy, little is known about their attitudes towards deprescribing. Objective This ...Open AccessArticle -
A systematic review of interventions to deprescribe benzodiazepines and other hypnotics among older people
Published 2017-01-01Purpose: Benzodiazepines are effective medicines for insomnia and anxiety but are commonly used beyond recommended treatment time frames, which may lead to adverse drug events. The aim of this systematic review was to ...Open AccessArticle -
Development and pilot testing of the revised Patients’ Attitudes Towards Deprescribing questionnaire for people with cognitive impairment
Published 2018-01-01Objectives: 1) To develop a version of the revised Patients’ Attitude Towards Deprescribing (rPATD) questionnaire for people with mild cognitive impairment and mild-to-moderate dementia (rPATDcog) and 2) capture the beliefs ...Open AccessArticle