The University of Sydney: Recent submissions
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PD-L1 expression in melanoma has prognostic significance but shows marked heterogeneity within and between patients- implications for anti-PD-1/PD-L1 clinical trials
Published 2015This study evaluated the expression of PD-L1 in immunotherapy-naive metastatic melanoma patients to determine longitudinal intrapatient concordance and correlate PD-L1 status with clinicopathologic characteristics and ...Open AccessArticle -
Adjuvant lymph-node field radiotherapy versus observation only in patients with melanoma at high risk of further lymph-node field relapse after lymphadenectomy (ANZMTG 01.02/TROG 02.01): 6-year follow-up of a phase 3, randomised controlled trial
Published 2015BACKGROUND: Adjuvant radiotherapy is recommended for patients with melanoma after lymphadenectomy. We previously showed this treatment reduced risk of repeat lymph-node field cancer in patients with a high risk of recurrence ...Open AccessArticle -
CD103(+) Tumor-Resident CD8(+) T Cells Are Associated with Improved Survival in Immunotherapy-Naive Melanoma Patients and Expand Significantly During Anti-PD-1 Treatment
Published 2018Purpose: Therapeutic blockade of immune checkpoints has revolutionized cancer treatment. Durable responses, however, occur in less than half of those treated, and efforts to improve treatment efficacy are confounded by a ...Open AccessArticle -
The Determinants of Research Culture: The Case of Indonesian Universities
Published 2025Pursuing its ambition to create world class universities, Indonesia has adopted a publish or perish strategy, encouraging academics to write and publish extensively to institutionalize a research culture. While this approach ...Open AccessThesis -
Towards a personalised theranostics platform through an improved understanding of the biological effects of radionuclide therapy
Published 2024The clinical incorporation of radiobiology into theranostic nuclear medicine for cancer treatment is still an emerging field. The complexities involved in personalising therapy using radionuclides must be investigated ...Open AccessThesis