Prognostic significance of FXYD-3 in Patients who underwent resection of Colorectal Liver Metastases
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Open Access
Type
ArticleAuthor/s
Bhimani, NazimAbstract
Background: Colorectal cancer (CRC) is the third most common cancer in Australia and approximately 50% of these patients will eventually develop colorectal liver metastases (CRLM) [1-3]. Many organs such as the breast, pancreas, lung, stomach and rectum have varying expression ...
See moreBackground: Colorectal cancer (CRC) is the third most common cancer in Australia and approximately 50% of these patients will eventually develop colorectal liver metastases (CRLM) [1-3]. Many organs such as the breast, pancreas, lung, stomach and rectum have varying expression levels of FXYD-3. There are conflicting results from studies examining the relationship between FXYD-3 expression and CRC, and to date there have been no studies on the expression of FXYD-3 in CRLM. Aims: The aim of this study is to determine the prevalence of FXYD-3 expression in patients with primary CRC and those that develop CRLM, and determine if FXYD-3 expression is associated with survival after resection of CRLM.
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See moreBackground: Colorectal cancer (CRC) is the third most common cancer in Australia and approximately 50% of these patients will eventually develop colorectal liver metastases (CRLM) [1-3]. Many organs such as the breast, pancreas, lung, stomach and rectum have varying expression levels of FXYD-3. There are conflicting results from studies examining the relationship between FXYD-3 expression and CRC, and to date there have been no studies on the expression of FXYD-3 in CRLM. Aims: The aim of this study is to determine the prevalence of FXYD-3 expression in patients with primary CRC and those that develop CRLM, and determine if FXYD-3 expression is associated with survival after resection of CRLM.
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Date
2019-05-03Licence
The author retains copyright of this thesis. It may only be used for the purposes of research and study. It must not be used for any other purposes and may not be transmitted or shared with others without prior permission.Faculty/School
Faculty of Medicine and HealthDepartment, Discipline or Centre
Biostatistics, School of Public HealthShare