Increased planned delivery contributes to declining rates of pregnancy hypertension in Australia: a population-based record linkage study

Abstract

Objective: Since the 1990s, pregnancy hypertension rates have declined in some countries but not all. Increasing rates of early planned delivery (before the due date) have been hypothesised as the reason for the decline. The aim of this study was to explore whether early planned delivery can partly explain the declining pregnancy hypertension rates in Australia. Design: Population-based record linkage study utilising linked birth and hospital records Setting and Participants: A cohort of 1,076,122 deliveries in New South Wales, Australia, 2001-2012. Outcome measures: Pregnancy hypertension (including gestational hypertension, preeclampsia and eclampsia) was the main outcome, preeclampsia was a secondary outcome Results: From 2001 to 2012, pregnancy hypertension rates declined by 22% from 9.9% to 7.7% and preeclampsia by 27% from 3.3% to 2.4% (trend P <0.0001). At the same time, planned deliveries increased: prelabour caesarean section by 43% (12.9% to 18.4%) and labour inductions by 10% (24.8% to 27.2%). Many maternal risk factors for pregnancy hypertension significantly increased (P<0.01) over the study period including nulliparity, age ≥35 years, diabetes, overweight and obesity, and use of assisted reproductive technologies; some risk factors decreased including multi-fetal pregnancies, age <20 years, autoimmune diseases and previous pregnancy hypertension. Given these changes in risk factors the pregnancy hypertension rate was predicted to increase to 10.5%. Examination of annual gestational age distributions showed that pregnancy hypertension rates actually declined from 38 weeks gestation and were steepest from 41 weeks; at least 36% of the decrease could be attributed to planned deliveries. The risk factors for pregnancy hypertension were also risk factors for planned delivery. Conclusions: It appears that an unanticipated consequence of increasing early planned deliveries is a decline in the incidence of pregnancy hypertension. Women with risk factors for hypertension were relatively more likely to be selected for early delivery.