|Title:||Red cell and platelet transfusions in neonates: a population based study|
|Authors:||Bowen, Jennifer R|
Patterson, Jillian A
Roberts, Christine L.
Isbister, James P
Irving, David O
Ford, Jane B
|Publisher:||BMJ Publishing Group Ltd & Royal College of Paediatrics and Child Health|
|Citation:||Bowen JR, Patterson JA, Roberts CL, Isbister JP, Irving DO, Ford JB. Red cell and platelet transfusions in neonates: a population based study. Arch Dis Child Fetal Neonatal Edition 2015; 100:F411-F415|
|Abstract:||Objectives: Reports of neonatal transfusion practices have focused predominantly on premature neonates admitted to neonatal intensive care units (NICU), however little is known about transfusion among other neonates. This study aimed to describe the use of blood products among all neonates. Design: Linked population-based birth and hospital discharge data from New South Wales (NSW), Australia was used to determine rates of blood product transfusion in the first 28 days of life. The study included all livebirths ≥23 weeks’ gestation in NSW between 2001 and 2011. Results: Between 2001-2011, 5326 of 989,491 live born neonates received a blood product transfusion (5.4 per 1000 births). Transfusion rates were 4.8 per 1000 for red cells, 1.3 per 1000 for platelets and 0.3 per 1000 for exchange transfusion. High transfusion rates were seen in neonates with prior in-utero transfusion (631/1000), congenital anomaly requiring surgery (440/1000) or haemolytic disorder (106/1000). Among transfused infants, 7% received transfusions in a hospital without a NICU. Of those transfused, 64% were born ≤32 weeks gestation (n=3384, 255/1000 births), with 96% of these receiving red cells. 36% were born >32 weeks gestation (n= 1942, 1.98/1000 births), with 76% receiving red cells and 38% receiving platelets. Conclusions: In this population based study, high transfusion rates were seen in neonates with haemolytic disorders or requiring surgery, as well as in those born preterm. Thirty-six percent of neonates who received blood products were born >32 weeks gestation and 7% were transfused in hospitals without a NICU.|
|Type of Work:||Article|
|Type of Publication:||Pre-print|
|Appears in Collections:||Healthy Start to Life|
|Bowen_2015_ACD_FN_NeonatalTransfusions_pre-proof.pdf||507.4 kB||Adobe PDF|
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