Browsing by author "Sterjovski, Jasminka"
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A common mechanism of clinical HIV-1 resistance to the CCR5 antagonist maraviroc despite divergent resistance levels and lack of common gp120 resistance mutations
Roche, Michael; Salimi, Hamid; Duncan, Renee; Wilkinson, Brendan L.; Chikere, Kelechi; Moore, Miranda S.; Webb, Nicholas E.; Zappi, Helena; Sterjovski, Jasminka; Flynn, Jacqueline K.; Ellett, Anne; Gray, Lachlan R.; Lee, Benhur; Jubb, Becky; Westby, Mike; Ramsland, Paul A.; Lewin, Sharon R.; Payne, Richard J.; Churchull, Melissa J.; Gorry, Paul R.Published 2013-04-20The CCR5 antagonist maraviroc (MVC) inhibits human immunodeficiency virus type 1 (HIV-1) entry by altering the CCR5 extracellular loops (ECL), such that the gp120 envelope glycoproteins (Env) no longer recognize CCR5. The ...Open AccessArticle -
Site-Selective Solid-Phase Synthesis of a CCR5 Sulfopeptide Library To Interrogate HIV Binding and Entry
Liu, Xuyu; Malins, Lara R.; Roche, Michael; Sterjovski, Jasminka; Duncan, Renee; Garcia, Mary L.; Barnes, Nadine C,; Anderson, David A.; Stone, Martin J.; Gorry, Paul R.; Payne, Richard J.Published 2014-06-25Tyrosine (Tyr) sulfation is a common post-translational modification that is implicated in a variety of important biological processes, including the fusion and entry of human immunodeficiency virus type-1 (HIV-1). A number ...Open AccessArticle
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