• Bridging the gaps in test interpretation of SARS-CoV-2 through Bayesian network modelling 

      Wu, Yue; Foley, David; Ramsay, Jessica; Woodberry, Owen; Mascaro, Steven; Nicholson, Ann E.; Snelling, Tom
      Published 2021
      Abstract In the absence of an established gold standard, an understanding of the testing cycle from individual exposure to test outcome report is required to guide the correct interpretation of severe acute respiratory ...
      Article
    • Core Outcome Measures for Trials in People With Coronavirus Disease 2019: Respiratory Failure, Multiorgan Failure, Shortness of Breath, and Recovery. 

      Tong, Allison; Baumgart, Amanda; Evangelidis, Nicole; Viecelli, Andrea K; Carter, Simon A; Azevedo, Luciano Cesar; Cooper, Tess; Bersten, Andrew; Cervantes, Lilia; Chew, Derek P; Crowe, Sally; Douglas, Ivor S; Flemyng, Ella; Elliott, Julian H; Hannan, Elyssa; Horby, Peter; Howell, Martin; Ju, Angela; Lee, Jaehee; Lorca, Eduardo; Lynch, Deena; Manera, Karine E; Marshall, John C; Gonzalez, Andrea Matus; McKenzie, Anne; Mehta, Sangeeta; Mer, Mervyn; Morris, Andrew Conway; Needham, Dale M; Nseir, Saad; Povoa, Pedro; Reid, Mark; Sakr, Yasser; Shen, Ning; Smyth, Alan R; Simpson, A John; Snelling, Tom; Strippoli, Giovanni F M; Teixeira-Pinto, Armando; Torres, Antoni; Turner, Tari; Webb, Steve; Williamson, Paula R; Woc-Colburn, Laila; Zhang, Junhua; Craig, Jonathan C
      Published 2021
      OBJECTIVES: Respiratory failure, multiple organ failure, shortness of breath, recovery, and mortality have been identified as critically important core outcomes by more than 9300 patients, health professionals, and the ...
      Article
    • Core Outcomes Set for Trials in People With Coronavirus Disease 2019. 

      Tong, Allison; Elliott, Julian H; Azevedo, Luciano Cesar; Baumgart, Amanda; Bersten, Andrew; Cervantes, Lilia; Chew, Derek P; Cho, Yeoungjee; Cooper, Tess; Crowe, Sally; Douglas, Ivor S; Evangelidis, Nicole; Flemyng, Ella; Hannan, Elyssa; Horby, Peter; Howell, Martin; Lee, Jaehee; Liu, Emma; Lorca, Eduardo; Lynch, Deena; Marshall, John C; Matus Gonzalez, Andrea; McKenzie, Anne; Manera, Karine E; McLeod, Charlie; Mehta, Sangeeta; Mer, Mervyn; Conway Morris, Andrew; Nseir, Saad; Povoa, Pedro; Reid, Mark; Sakr, Yasser; Shen, Ning; Smyth, Alan R; Snelling, Tom; Strippoli, Giovanni Fm; Teixeira-Pinto, Armando; Torres, Antoni; Turner, Tari; Viecelli, Andrea K; Webb, Steve; Williamson, Paula R; Woc-Colburn, Laila; Zhang, Junhua; Craig, Jonathan C
      Published 2020
      OBJECTIVES: The outcomes reported in trials in coronavirus disease 2019 are extremely heterogeneous and of uncertain patient relevance, limiting their applicability for clinical decision-making. The aim of this workshop ...
      Article
    • COVID-19 public health measures and respiratory syncytial virus 

      Britton, Philip N; Hu, Nan; Saravanos, Gemma; Shrapnel, Jane; Davis, Jake; Snelling, Tom; Dalby-Payne, Jacqui; Kesson, Alison M; Wood, Nicholas; Macartney, Kristine; McCullagh, Cheryl; Lingam, Raghu
      Published 2020
      Article
    • International Survey to Establish Prioritized Outcomes for Trials in People With Coronavirus Disease 2019. 

      Evangelidis, Nicole; Tong, Allison; Howell, Martin; Teixeira-Pinto, Armando; Elliott, Julian H; Azevedo, Luciano Cesar; Bersten, Andrew; Cervantes, Lilia; Chew, Derek P; Crowe, Sally; Douglas, Ivor S; Flemyng, Ella; Horby, Peter; Lee, Jaehee; Lorca, Eduardo; Lynch, Deena; Marshall, John C; McKenzie, Anne; Mehta, Sangeeta; Mer, Mervyn; Conway Morris, Andrew; Nseir, Saad; Povoa, Pedro; Reid, Mark; Sakr, Yasser; Shen, Ning; Smyth, Alan R; Snelling, Tom; Strippoli, Giovanni F M; Torres, Antoni; Turner, Tari; Webb, Steve; Williamson, Paula R; Woc-Colburn, Laila; Zhang, Junhua; Baumgart, Amanda; Cabrera, Sebastian; Cho, Yeoungjee; Cooper, Tess; Guha, Chandana; Liu, Emma; Gonzalez, Andrea Matus; McLeod, Charlie; Natale, Patrizia; Saglimbene, Valeria; Viecelli, Andrea K; Craig, Jonathan C
      Published 2020
      OBJECTIVES: There are over 4,000 trials conducted in people with coronavirus disease 2019. However, the variability of outcomes and the omission of patient-centered outcomes may diminish the impact of these trials on ...
      Article
    • Modeling COVID-19 disease processes by remote elicitation of causal Bayesian networks from medical experts 

      Mascaro, Steven; Wu, Yue; Woodberry, Owen; Nyberg, Erik P.; Pearson, Ross; Ramsay, Jessica; Mace, Ariel; Foley, David; Snelling, Tom; Nicholson, Ann E.
      Published 2022
      Background COVID-19 is a new multi-organ disease, caused by the SARS-CoV-2 virus, resulting in considerable worldwide morbidity and mortality. While many recognized pathophysiological mechanisms are involved, their exact ...
      Preprint
    • OPTimising IMmunisation Using Mixed schedules (OPTIMUM): comparing allergic outcomes in infants following pertussis vaccination dataset 

      Snelling, Tom
      Published 2024-03-15
      OPTIMUM is an investigator-initiated phase IV, two-stage, multisite, parallel, double-blind, adaptive, randomised controlled trial of a single dose of DTwP given at the age of 6 to <12 weeks, followed by DTaP at 4 and 6 ...
      Open Access
      Dataset
    • Perspectives of patients, family members, health professionals and the public on the impact of COVID-19 on mental health. 

      Gardiner, Evangeline; Baumgart, Amanda; Tong, Allison; Elliott, Julian H; Azevedo, Luciano Cesar; Bersten, Andrew; Cervantes, Lilia; Chew, Derek P; Cho, Yeoungjee; Crowe, Sally; Douglas, Ivor S; Evangelidis, Nicole; Flemyng, Ella; Horby, Peter; Howell, Martin; Lee, Jaehee; Lorca, Eduardo; Lynch, Deena; Marshall, John C; Gonzalez, Andrea Matus; McKenzie, Anne; Manera, Karine; Mehta, Sangeeta; Mer, Mervyn; Morris, Andrew Conway; Nseir, Saad; Povoa, Pedro; Reid, Mark; Sakr, Yasser; Shen, Ning; Smyth, Alan R; Snelling, Tom; Strippoli, Giovanni F M; Teixeira-Pinto, Armando; Torres, Antoni; Viecelli, Andrea K; Webb, Steve; Williamson, Paula R; Woc-Colburn, Laila; Zhang, Junhua; Craig, Jonathan C
      Published 2022
      BACKGROUND: The coronavirus (COVID-19) pandemic has seen a global surge in anxiety, depression, post-traumatic stress disorder (PTSD), and stress. AIMS: This study aimed to describe the perspectives of patients with COVID-19, ...
      Article