Browsing by author "Shi, Mang"
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Co-infecting pathogens can contribute to inflammatory responses and severe symptoms in COVID-19
Chen, Liping; Shen, Lihan; Wu, Weichen; Guan, Wenda; Zhou, Jinchao; Luo, Gengyan; Chen, Qimin; Zhou, Hongxia; Deng, Zhenxuan; Chen, Yaoqing; Zhao, Wenjing; Jin, Wenxiang; Qiu, Minshan; Zheng, Qianwei; Wang, Yutao; Liu, Chen; Bai, Xiangxiang; Guo, Deyin; Holmes, Edward C.; Zhong, Nanshan; Shi, Mang; Yang, ZifengPublished 2022Background: The current COVID-19 pandemic is posing a major challenge to public health on a global scale. While it is generally believed that severe COVID-19 results from over-expression of inflammatory mediators (i.e., a ...Article -
The enteric virome of cats with feline panleukopenia differs in abundance and diversity from healthy cats
Barrs, Vanessa; Brussel, Kate Van; Wang, Xiuwan; Shi, Mang; Carrai, Maura; Feng, Shuo; Li, Jun; Holmes, Edward; Beatty, JuliaPublished 2022Feline panleukopenia (FPL) is a severe, often fatal disease caused by feline parvovirus (FPV). How infection with FPV might impact the composition of the entire eukaryotic enteric virome in cats has not been characterized. ...Preprint -
High resolution metagenomic characterization of complex infectomes in paediatric acute respiratory infection
Li, Ci-Xiu; Li, Wei; Zhou, Jun; Zhang, Bing; Feng, Yan; Xu, Chang-Ping; Lu, Yi-Yu; Holmes, Edward C.; Shi, MangPublished 2020The diversity of pathogens associated with acute respiratory infection (ARI) makes diagnosis challenging. Traditional pathogen screening tests have a limited detection range and provide little additional information. We ...Article -
Host age shapes virome abundance and diversity in birds
Wille, Michelle; Shi, Mang; Hurt, Aeron C.; Klaassen, Marcel; Holmes, Edward C.Published 2020Abstract Host age influences the ecology of many microorganisms. This is evident in one-host – one virus systems, such as influenza A virus in Mallards, but also in community studies of parasites and microbiomes. We used ...Preprint -
Meta-transcriptomic analysis of virus diversity in urban wild birds with paretic disease
Chang, Wei-Shan; Eden, John-Sebastian; Hall, Jane; Shi, Mang; Rose, Karrie; Holmes, Edward C.Published 2020Wild birds are major natural reservoirs and potential dispersers of a variety of infectious diseases. As such, it is important to determine the diversity of viruses they carry and use this information to help understand ...Preprint -
Pathogen discovery and new perspectives on virus evolution
Shi, MangPublished 2015-03-01Viruses are ubiquitous, with a genetic and phenotypic diversity that surpasses any other group of organisms. Despite this, relatively little is known about the evolutionary history that has generated this remarkable ...USyd AccessThesis -
Total infectome characterization of respiratory infections in pre-COVID-19 Wuhan, China
Shi, Mang; Zhao, Su; Yu, Bin; Wu, Wei-Chen; Hu, Yi; Tian, Jun-Hua; Yin, Wen; Ni, Fang; Hu, Hong-Ling; Geng, Shuang; Tan, Li; Peng, Ying; Song, Zhi-Gang; Wang, Wen; Chen, Yan-Mei; Holmes, Edward C.; Zhang, Yong-ZhenPublished 2022At the end of 2019 Wuhan witnessed an outbreak of "atypical pneumonia" that later developed into a global pandemic. Metagenomic sequencing rapidly revealed the causative agent of this outbreak to be a novel coronavirus ...Article -
Total Infectomes Characterization of Respiratory Infections in pre-COVID-19 Wuhan, China
Shi, Mang; Zhao, Su; Yu, Bin; Wu, Wei-Chen; Hu, Yi; Tian, Jun-Hua; Yin, Wen; Ni, Fang; Hu, Hong-Ling; Geng, Shuang; Tan, Li; Peng, Ying; Song, Zhi-Gang; Wang, Wen; Chen, Yan-Mei; Holmes, Edward C.; Zhang, Yong-ZhenPublished 2021At the end of 2019 Wuhan witnessed an outbreak of “atypical pneumonia” that later developed into a global pandemic. Metagenomic sequencing rapidly revealed the causative agent of this outbreak to be a novel coronavirus - ...Preprint -
Total virome characterizations of game animals in China reveals a spectrum of emerging viral pathogens
He, Wan-Ting; Hou, Xin; Zhao, Jin; Sun, Jiumeng; He, Haijian; Si, Wei; Wang, Jing; Jiang, Zhiwen; Yan, Ziqing; Xing, Gang; Lu, Meng; Suchard, Marc A.; Ji, Xiang; Gong, Wenjie; He, Biao; Li, Jun; Lemey, Philippe; Guo, Deyin; Tu, Changchun; Holmes, Edward C.; Shi, Mang; Su, ShuoPublished 2021Game animals are wildlife species often traded and consumed as exotic food, and are potential reservoirs for SARS-CoV and SARS-CoV-2. We performed a meta-transcriptomic analysis of 1725 game animals, representing 16 species ...Preprint -
Virome characterization of game animals in China reveals a spectrum of emerging pathogens
He, Wan-Ting; Hou, Xin; Zhao, Jin; Sun, Jiumeng; He, Haijian; Si, Wei; Wang, Jing; Jiang, Zhiwen; Yan, Ziqing; Xing, Gang; Lu, Meng; Suchard, Marc A.; Ji, Xiang; Gong, Wenjie; He, Biao; Li, Jun; Lemey, Philippe; Guo, Deyin; Tu, Changchun; Holmes, Edward C.; Shi, Mang; Su, ShuoPublished 2022Game animals are wildlife species traded and consumed as food, and potential reservoirs for SARS-CoV and SARS-CoV-2. We performed a meta-transcriptomic analysis of 1941 game animals, representing 18 species and five mammalian ...Article
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