Now showing items 1-3 of 3

    • Imaging mass spectrometry of frontal white matter lipid changes in human alcoholics 

      de la Monte, SM; Kay, J; Yalcin, EB; Kril, JJ; Sheedy, D; Sutherland, GT (Alcohol (Fayetteville, N.Y.), 2018)
      BACKGROUND: Chronic alcohol use disorders (AUD) are associated with white matter (WM) degeneration with altered myelin integrity. Matrix assisted laser desorption ionization-imaging mass spectrometry (MALDI-IMS) enables ...
    • Neuropathology of alcoholism 

      Sutherland, GT; Sheedy, D; Kril, JJ (Handbook of clinical neurology, 2014)
      Chronic alcohol consumption results in structural changes to the brain. In alcoholics without coexisting thiamine deficiency or liver disease this is largely restricted to a loss of white-matter volume. When it occurs, ...
    • Re-investigating the effects of chronic smoking on the pathology of alcohol-related human brain damage 

      McCorkindale, AN; Sizemova, A; Sheedy, D; Kril, JJ; Sutherland, GT (Alcohol (Fayetteville, N.Y.), 2018-07)
      Both pathological and neuroimaging studies have shown that chronic alcohol abuse causes generalized white matter, but limited gray matter, volume loss. Recent neuroimaging studies suggest that tobacco smoking also causes ...