Browsing by author "Sheedy, D"
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Imaging mass spectrometry of frontal white matter lipid changes in human alcoholics
de la Monte, SM; Kay, J; Yalcin, EB; Kril, JJ; Sheedy, D; Sutherland, GTPublished 2018-01-01BACKGROUND: Chronic alcohol use disorders (AUD) are associated with white matter (WM) degeneration with altered myelin integrity. Matrix assisted laser desorption ionization-imaging mass spectrometry (MALDI-IMS) enables ...Open AccessArticle -
Neuropathology of alcoholism
Sutherland, GT; Sheedy, D; Kril, JJPublished 2014-01-01Chronic alcohol consumption results in structural changes to the brain. In alcoholics without coexisting thiamine deficiency or liver disease this is largely restricted to a loss of white-matter volume. When it occurs, ...Open AccessArticle -
Re-investigating the effects of chronic smoking on the pathology of alcohol-related human brain damage
McCorkindale, AN; Sizemova, A; Sheedy, D; Kril, JJ; Sutherland, GTPublished 2018-07-01Both pathological and neuroimaging studies have shown that chronic alcohol abuse causes generalized white matter, but limited gray matter, volume loss. Recent neuroimaging studies suggest that tobacco smoking also causes ...Open AccessArticle
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